Search found 7504 matches
- Tue Jan 30, 2024 4:47 am
- Forum: Prevention and Treatment
- Topic: Celebration Thread! Biogen is going to the FDA with Aducan.
- Replies: 1808
- Views: 381028
Re: Celebration Thread! Biogen is going to the FDA with Aducan.
I respectfully have a different view: that J11--and I for that matter--are not celebrating drugs; we are celebrating progress in identifying SOME--but not all--drivers of Alzheimer's pathology, specifically amyloid and tau, which seem more prevalent and more toxic in ApoE 4 carriers an earlier age,...
- Sun Jan 28, 2024 10:34 am
- Forum: Prevention and Treatment
- Topic: Is there research showing benefit of low fat diet for apoe4 phenotype?
- Replies: 14
- Views: 3897
Re: Is there research showing benefit of low fat diet for apoe4 phenotype?
Hello, Does anyone on this forum know of published research that suggests that a low fat diet (all fat, not just saturated) is helpful for mitigating cardio vascular disease for those with apoE4 phenotypes? Great question. A low fat diet was the original recommended diet for our phenotype when we b...
- Sat Jan 27, 2024 2:24 pm
- Forum: Prevention and Treatment
- Topic: "Their Alzheimer's Disease Didn't Worsen. Why?"
- Replies: 3
- Views: 1677
Re: "Their Alzheimer's Disease Didn't Worsen. Why?"
I doubt we all need to buy Peloton machines or become tennis pros. It seems to the level of sustained activity over a long period of time, not one specific activity, that MAY be important for people with MCI. Presumably diet, sleep, social supports, etc. also were in good shape for these men, but w...
- Sat Jan 27, 2024 2:11 pm
- Forum: Prevention and Treatment
- Topic: p tau217
- Replies: 5
- Views: 1669
Re: p tau217
Has anyone found a way to get a p-tau217 test? Dr. Bredesen is very excited about this one and is partnering with a company to release a fairly inexpensive version soon. The hype about the new/cheap test seems to be making the blood test the diagnostic gold standard. That seems to be the current co...
- Sat Jan 27, 2024 1:56 pm
- Forum: Announcements and Events
- Topic: Announcing a Personalized Precision Medicine Clinical Trial to Reverse Dementia
- Replies: 42
- Views: 172973
Re: Announcing a Personalized Precision Medicine Clinical Trial to Reverse Dementia
I finally found a doctor that would order my labs. Going today. Do you have a recommendation of a health coach that is not super expensive that can help me with the food to eat. Or a cook book the site you gave me from Apollo has a picture I need more than that. I know there is a list of doctors an...
- Sat Jan 27, 2024 11:46 am
- Forum: Getting Started
- Topic: Panicking 41yr old grown up man
- Replies: 15
- Views: 38211
Re: Panicking 41yr old grown up man
Instead my results were very favorable. I was recruited for a project to see if I had a genetic reason for how well I was doing and they would like to have blood tests and my brain when I die. Both are fine with me. They would like a spinal test and I said no to that. I have not been a devoted foll...
- Tue Jan 16, 2024 8:12 am
- Forum: Prevention and Treatment
- Topic: Alzheimer's Disease Cured ! J11 Exclusive!
- Replies: 15
- Views: 17762
Re: Alzheimer's Disease Cured ! J11 Exclusive!
I can well understood how yelling "Cure" in a crowded theater is frowned upon, though considering the current evidence I feel that not yelling "Cure" given the millions of people at risk and unaware of their risk also has certain moral implications. I am very very uncomfortable ...
- Sun Jan 14, 2024 11:29 am
- Forum: Prevention and Treatment
- Topic: Celebration Thread! Biogen is going to the FDA with Aducan.
- Replies: 1808
- Views: 381028
Re: Celebration Thread! Biogen is going to the FDA with Aducan.
Yes, I've wondered the same and sincerely hope this will pan out to protect more E4 carriers.I have wondered if the titration schedule is one reason why we haven't heard of very severe adverse events or deaths in AHEAD, in addition to starting at an earlier disease stage, with possibly less CAA.
- Sun Jan 14, 2024 11:25 am
- Forum: Science and Research
- Topic: Dha and lpc dha associated with worse AD progression??
- Replies: 9
- Views: 32657
Re: Dha and lpc dha associated with worse AD progression??
There may be an interaction between omega3 fatty acids and homocysteine with regard to brain health. See for example https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464144/ If one of the main effects of DHA on cognition is to make B-vitamins more effective in the brain they can only be protective if ...
- Fri Jan 12, 2024 8:34 am
- Forum: Prevention and Treatment
- Topic: Celebration Thread! Biogen is going to the FDA with Aducan.
- Replies: 1808
- Views: 381028
Re: Celebration Thread! Biogen is going to the FDA with Aducan.
I learned of this at my most recent infusion; not every person in the trial has even been notified yet since it is a December revision in the IRB consent. Thanks for sharing these updates, NF52. I imagine that this will skew the numbers in the original dataset if enough people drop out of the contr...