Search found 2552 matches

by SusanJ
Sun Jun 22, 2014 8:46 pm
Forum: Science and Research
Topic: Review: HDL and cholesterol handling in the brain.
Replies: 52
Views: 21845

Re: Review: HDL and cholesterol handling in the brain.

WA, add in a little olive oil, avocado and nuts, too. We'd like to keep you in this existence a little longer. :) Oleic acid modulates mRNA expression of liver X receptor (LXR) and its target genes ABCA1 and SREBP1c in human neutrophils. http://www.ncbi.nlm.nih.gov/pubmed/24722912 Tomorrow isn't my ...
by SusanJ
Sun Jun 22, 2014 5:23 pm
Forum: Science and Research
Topic: Review: HDL and cholesterol handling in the brain.
Replies: 52
Views: 21845

Re: Review: HDL and cholesterol handling in the brain.

And for today's genetic lottery, and a possible reason why some early drugs have failed... Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's disease. Taken together, the results of the present study suggest that rs7120118 polymorphism in NR...
by SusanJ
Sun Jun 22, 2014 2:33 pm
Forum: Science and Research
Topic: Review: HDL and cholesterol handling in the brain.
Replies: 52
Views: 21845

Re: Review: HDL and cholesterol handling in the brain.

My apologies in advance, but this will be a REALLY long post. I normally would restrain myself, but this stuff seems important and relevant. The article I found took some concentration and patience to get through, so I decided to pull out the relevant passages for the Cliff Notes (sort of) version. ...
by SusanJ
Sat Jun 21, 2014 7:20 pm
Forum: Science and Research
Topic: Review: HDL and cholesterol handling in the brain.
Replies: 52
Views: 21845

Re: Review: HDL and cholesterol handling in the brain.

The full text is available pre-press through the IOS link in PubMed. Heres the direct link.

xhttp://iospress.metapress.com/content/gr7907327h815467/fulltext.pdf
by SusanJ
Sat Jun 21, 2014 11:06 am
Forum: The Social Hour
Topic: Alzheimer's Longest Day 6/21/14
Replies: 6
Views: 3638

Re: Alzheimer's Longest Day 6/21/14

"...doing what they love to honor those facing Alzheimer's."

I'm a science geek, and I'm guessing there are others on this forum that are, too. So, I'd say we make a great team for the Longest Day challenge, doing research for ourselves and our families. :D
by SusanJ
Sat Jun 21, 2014 7:40 am
Forum: Our Stories
Topic: New Test Results: CAC Score and LDL-P
Replies: 133
Views: 53901

Re: New Test Results: CAC Score and LDL-P

Russ, I agree with Lilly. Find a good cardiologist and get on a statin. I'm not big on taking drugs, but please don't mess with the blockages by fiddling around the edges. Get on a statin, and then fiddle around the edges. A good cardiologist can help you fiddle. You don't want a heart attack on the...
by SusanJ
Fri Jun 20, 2014 8:59 pm
Forum: The Social Hour
Topic: Fat Head Friday Party
Replies: 2
Views: 2098

Re: Fat Head Friday Party

I went with the dark chocolate fix. :D
by SusanJ
Fri Jun 20, 2014 8:58 pm
Forum: Science and Research
Topic: Review: HDL and cholesterol handling in the brain.
Replies: 52
Views: 21845

Re: Review: HDL and cholesterol handling in the brain.

WA, I totally expected you to jump on the MMP connection. ;) Besides curcumin/tumeric, you can look to HDIs (HDAC inhibitors) to downregulate MMP and NF Kappa B. I've looked at these because there is some RA research that says HDIs could help reduce joint erosions by inhibiting this same MMP degrada...
by SusanJ
Sun Jun 15, 2014 6:44 pm
Forum: Prevention and Treatment
Topic: Bioelectronics
Replies: 6
Views: 2870

Re: Bioelectronics

Nuttin' and that's why I'm asking.
by SusanJ
Sun Jun 15, 2014 2:46 pm
Forum: Prevention and Treatment
Topic: Bioelectronics
Replies: 6
Views: 2870

Bioelectronics

Holy Fantastic Voyage ... Came across this in one of my RA feeds. Can the Nervous System Be Hacked? http://www.nytimes.com/2014/05/25/magazine/can-the-nervous-system-be-hacked.html A neurosurgeon, and also Feinstein Institute’s president, Tracey had spent more than a decade searching for a link betw...