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by JimBG
Thu May 31, 2018 1:56 pm
Forum: Prevention and Treatment
Topic: Another negative lipid profile trend
Replies: 45
Views: 14210

Re: Another negative lipid profile trend

As an update I saw a cardiologist today. I frankly felt more informed than him. Long story short as Stavia indicted the recommendation was a statin and aspirin. He felt that APOE status, lack of symptoms and some good biomarkers showing low inflammation and insulin receptivity does not change his re...
by JimBG
Wed May 30, 2018 6:54 pm
Forum: Prevention and Treatment
Topic: Simvastatin and the ApoE4 Allele
Replies: 31
Views: 9950

Re: Simvastatin and the ApoE4 Allele

Thanks to all for the references. This is certainly a complicated topic with much to digest. I found the "What the Cardiologist Should" piece particularly interesting arguing that statins could help prevent AD if introduced early enough but are ineffective in treating it. Also that the evi...
by JimBG
Wed May 30, 2018 8:51 am
Forum: Prevention and Treatment
Topic: Simvastatin and the ApoE4 Allele
Replies: 31
Views: 9950

Simvastatin and the ApoE4 Allele

This is probably old news for many but I thought this article in Circulation was quite interesting. it's conclusion was: " —Myocardial infarction survivors with the e 4 allele have a nearly 2-fold increased risk of dying compared with other patients, and the excess mortality can be abolished by...
by JimBG
Tue May 29, 2018 4:52 pm
Forum: Prevention and Treatment
Topic: LDL and fats, two new studies
Replies: 7
Views: 2595

Re: LDL and fats, two new studies

What are relevant biomarkers I can follow? Hi Verax I am struggling with the same issues you have outlined, as many here are as well. My T Cholesterol and LDL C have increased since I have lost weight, began intermittent fasting, and sustained a mild ketosis. I recently got a NMR blood test that wa...
by JimBG
Mon May 28, 2018 7:26 pm
Forum: Prevention and Treatment
Topic: Another negative lipid profile trend
Replies: 45
Views: 14210

Re: Another negative lipid profile trend

Thanks Katie for your input. Agree in the need for serial advanced lipids. And as I understand it certain lipid ratios are more predictive of risk than absolute numbers, and overtime can help determine if one is making progress.
by JimBG
Mon May 28, 2018 11:43 am
Forum: Prevention and Treatment
Topic: Another negative lipid profile trend
Replies: 45
Views: 14210

Re: Another negative lipid profile trend

Thanks Stavia. Very much appreciate your balanced perspective. Am going through the threads on statins, calcium scoring and plaque reduction. Also reading Ivor Cummings book "Eat Rich Live Long" and watched "The Widowmaker". Lots to read and consider. After I feel comfortable tha...
by JimBG
Thu May 24, 2018 1:10 pm
Forum: Prevention and Treatment
Topic: Another negative lipid profile trend
Replies: 45
Views: 14210

Re: Another negative lipid profile trend

Got my calcium score today, my first one, and unfortunately it was 175. That puts me at the moderate evidence level for CVD. Also based upon my age, sex and race, I am at the 69th percentile, not good either. The test was done on a CT Scanner with automatic exposure control, hence my radiation dose ...
by JimBG
Mon May 21, 2018 2:17 pm
Forum: Science and Research
Topic: Sulforphane clears amyloid plaques and tau tangles
Replies: 21
Views: 6842

Sulforphane clears amyloid plaques and tau tangles

Interesting study showing sulforaphane, which is high in broccoli sprouts, clears away brain amyloid plaques and tau tangles and ameliorated memory defects in mice engineered to get Alzheimer's disease. Dr. Rhonda Patrick has touted the benefits of sulforaphane for a quite while now and I recently s...
by JimBG
Wed Apr 25, 2018 6:02 pm
Forum: Science and Research
Topic: Intermittent Fasting Rat Study
Replies: 1
Views: 1074

Intermittent Fasting Rat Study

Don't know if this has been covered but interesting study showing the positive effect of IF on cognitive function and dyslipidemia in Alzheimer's disease-induced estrogen deficient rats.

https://www.ncbi.nlm.nih.gov/m/pubmed/29307281/
by JimBG
Tue Apr 10, 2018 5:37 pm
Forum: Prevention and Treatment
Topic: Skipped Meals and Memory
Replies: 1
Views: 844

Skipped Meals and Memory

Interesting article on fasting, ketones and impact on longevity, healthspan and age related cognitive decline based on findings published in September 2017.

http://www.northbaybusinessjournal.com/northbay/marincounty/8183827-181/buck-institute-research-aging-fasting-memory

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