Andru, The evolving scientific literature is more reliable than expert opinion. An active young athlete, especially one who regularly does high intensity interval training, gets huge benefits in terms of cognition, mood, neurogenesis, angiogenesis and metabolism. This might well limit the influence ...

Our bodies evolved to be healthy when use food produced by nature, and I think that is the truly safest place to start. Perhaps the question faced by many people is: Are some foods produced by nature more beneficial or harmful to health than others, in terms of quality of life, disability or premat...

Personally, I've done the genetic testing (under my real name - something I now regret) and also bought long-term care insurance (thankfully, before my status was known). Thanks, Coach DD. That seems to be wise. Based on experiences narrated by people, it seems advisable to buy long-term care insur...

I had a 30 year career in the healthcare insurance industry (I negotiated the contracts with doctors), so I may be able to help. CoachDD, It would be great to have your opinion on a practical matter. Genetic testing. Long-term care insurance cover. Does it make a difference in which order these are...

Interesting discussion. This information might be helpful, despite its limitations and caveats: https://www.ncbi.nlm.nih.gov/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Click%20on%20image%20to%20zoom&p=PMC3&id=5081717_ajcn134460fig1.jpg from https://www.ncbi.nlm.nih.gov/pmc/...

Hi all, Is the point of these diet and lifestyle interventions to get your labs to optimal levels? If I've been told my lab tests reflect envious levels, from aeop4.info members, does that mean I just keep on keeping on with what I've been doing because its working and just enjoy life? Thanks Shach...

I'm sharing all of this to enlighten others who read this post and are concerned about early onset - just because AD is not in your family history, that does NOT mean you are not at risk (especially if you carry one or two ApoE4 allele along with the other gene markers). I welcome any and all feedb...

S Bean,

Thanks for sharing your wise thoughts and moving experiences. You are an inspiration.

Great to have you here.

Happy for you, giftsplash! This community does so many good things for so many people. One of them could perhaps be educating people about the reliability/unreliability of direct-to-consumer genetic tests. Another could be educating doctors about the need for fully informed consent and quality contr...

The APOE4 allele affects gray matter volume in specific brain regions of infants. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056558/figure/F3/ APOE targeted replacement (TR) mice show different dendritic spine density depending on the APOE allele. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846...