Search found 56 matches

by antimatter37
Mon Oct 22, 2018 1:31 pm
Forum: Science and Research
Topic: Herpes and other viruses the root cause?
Replies: 15
Views: 7459

Re: Herpes and other viruses the root cause?

Here is a newer review article on the correlation between HSV and AD in APOE 4 carriers. From the abstract: "Strong evidence has emerged recently for the concept that herpes simplex virus type 1 (HSV1) is a major risk for Alzheimer’s disease (AD). This concept proposes that latent HSV1 in brain...
by antimatter37
Tue Aug 21, 2018 11:59 am
Forum: Science and Research
Topic: APOE4 men lower risk than women for AD?
Replies: 5
Views: 2930

Re: APOE4 men lower risk than women for AD?

Here is an article from researchers at USC looking at this topic.

https://news.usc.edu/108027/why-does-al ... -than-men/

Since this work was published, there has not been significant follow-up by any other groups as far as I can tell.
by antimatter37
Tue May 22, 2018 12:11 pm
Forum: Science and Research
Topic: Move over Ubiquinol
Replies: 5
Views: 2880

Re: Move over Ubiquinol

It always bothers me a bit when one of the study authors happens to be on the board of the company that makes or licenses the stuff
(Antipodean Pharmaceuticals, Inc.).
by antimatter37
Thu Apr 26, 2018 6:14 pm
Forum: Prevention and Treatment
Topic: NAD/niacinamide
Replies: 32
Views: 18962

Re: NAD/niacniamide

I think the goal of both recommendations is to increase the amount of NAD (nicotinamide adenine dinucleotide) in the body. I too find the terminology surrounding NAD and its precursors confusing. Here is why I think the two recommendations are really the same thing: 1. Niacinamide (also known as nic...
by antimatter37
Wed Apr 11, 2018 5:36 pm
Forum: Science and Research
Topic: Erasing the damage caused by apoE4 in human genes? New study by Gladstone Institutes
Replies: 29
Views: 11803

Re: Erasing the damage caused by apoE4 in human genes? New study by Gladstone Institutes

Was able to pull the full article and read it over. I agree with others that this work does a very thorough job of explaining the detrimental role of APOE4 in human neurons. It reads like a horror story in that regard! The small molecule structure corrector for APOE4, ph002, is a real curiosity, als...
by antimatter37
Fri Apr 06, 2018 12:35 pm
Forum: Science and Research
Topic: Neurogenesis article
Replies: 3
Views: 1865

Re: Neurogenesis article

Thanks Orangeblossom. It seems logical that if there were to ever to be the ability to actually reverse an existing AD situation it would need to somehow involve the ability to bring new neurons and their associated biological support infrastructure into operation. The article claiming the detection...
by antimatter37
Wed Mar 28, 2018 11:29 am
Forum: Prevention and Treatment
Topic: Exercise and APOE4
Replies: 6
Views: 3114

Re: Exercise and APOE4

Thanks Katie - I was not aware of his APOE status, but if anyone really wants to start a lively conversation here just bring up the topic of statins and Alzheimer's!
by antimatter37
Wed Mar 28, 2018 9:59 am
Forum: Prevention and Treatment
Topic: Exercise and APOE4
Replies: 6
Views: 3114

Re: Exercise and APOE4

I agree fully that exercise must be at the top of any preventative strategy. Today, in an interview on CNBC entitled "Genome pioneer Craig Venter is trying to decode death" the first person to fully decode the human genome (in 2000) talks about genomics and all forms of disease, especially...
by antimatter37
Sat Mar 24, 2018 7:51 pm
Forum: Prevention and Treatment
Topic: Exercise and APOE4
Replies: 6
Views: 3114

Exercise and APOE4

For those of us APOE4 carriers (I am 4/4), there are many factors that we need to consider in order to attempt to mitigate or partially mitigate our unfortunate genetic inheritance. One of those factors is exercise. While there are numerous studies of various kinds that find positive correlations be...
by antimatter37
Sat Mar 24, 2018 7:43 pm
Forum: Prevention and Treatment
Topic: Interpreting 23andMe Results?
Replies: 2
Views: 1633

Re: Interpreting 23andMe Results?

Hi Andru - Look like you are trying to find results related to MTHFR gene. For $5, you can run your 23andme raw data through "Promethease", which will give you the result you are looking for. Just go to Promethease.com and have a look. It gives more comprehensive results that the 23andme s...