4th quarter 2023 In addition to this website, we (ApoE4.info) have a Facebook page https://www.facebook.com/apoe4.info where current research/articles or just items of interest to ApoE4s are posted. The posts are available to all whether or not a person has a Facebook account. Here are the Facebook...

Amyloid plaque reduction does not equal a cure for Alzheimer's. The amyloid hypothesis has yet to be validated, and over the years has only experienced greater and greater criticism especially after one of the most cited Alzheimer’s studies that underpins a key element of the amyloid hypothesis of A...

I use Theodent toothpaste. "Fluoride-Free, Natural Toothpaste for Remineralization and Sensitivity Reduction" Gluten Free, Sodium Lauryl Sulfate Free free, Vegan Here's their webite: https://shoptheodent.com/ Available on Amazon (other sources too, I'm sure): https://www.amazon.com/THEODEN...

J11

Alzheimer's disease has not been cured. In the future please be more cautious about promoting information that is misleading, providing undue hope.

As I have written before in these forums, the scientific community has critical voices about drug manufacturers not being completely forthcoming with information from their clinical trials. Here’s another on e this one referring to Donanemab with ApoE4 at the center of the target. Published two days...

This is another result from CTAD of interest. It shows amyloid removal by e3/e4 genotype. But is that a good thing? I'm not saying I don't recognize the toxic effects of amyloid, however, the amyloid hypothesis has been questioned for years and such questions only grew when it was revealed that one...

I wish we had mandated protections in place. Is this something we can push the FDA for? I too wish we had mandated protections in place to protect our fellow 4/4s, but this has already been attempted. Only after aducanumab/aduhelm approval, did the FDA update its safety-related labeling for ApoE ε4...

this woman's death is tragic. I shared this because our mission “is dedicated to understanding the APOE-ε4 allele and how it affects health.” Here's the Appropriate Use Recommendations on ARIA monitoring, especially in ApoE 4/4 Yes, not only are ε4 carriers, especially APOE4 homozygotes at higher r...

Just published (12 December 2023) Fatal iatrogenic cerebral β-amyloid-related arteritis in a woman treated with lecanemab for Alzheimer’s disease Definition of iatrogenic: Due to the activity of a physician or therapy. For example, an iatrogenic illness is an illness that is caused by a medication o...

Thank you so much for having me, I'm very glad to found this forum. Welcome. In addition to this web page's forums and wiki as pointed out by our support intern, you might also be interested in the ApoE4.info Facebook page, https://www.facebook.com/apoe4.info. Everyday there are posts of encouragem...