I've never looked into COMT and depression or AD. Not only that, I now need to read about COMT, knowing essentially nothing about it at present. @Julie - I hope I was clear that I'm saying there are many roads to depression. I'm not saying the allergic reaction angle is not right, just that there ar...

It is an interesting notion that depression can be caused by an allergic reaction or some other inflammatory condition. I see some hints of support for this, but we should view these kinds of articles with some skepticism. Depression is most clearly a multi-factorial condition. Solid research has es...

Russ -- +1 for the veggie oil study and meta-analysis.

Lance, What about this study screams poorly designed and executed, wasted tax money? Is it your belief that glycemic index or load as main variables are irrelevant, but that it is the timing that matters? It is easy to poke at clinical trials saying they did not do a specific permutation and dismiss...

I also love my new Instant Pot - about to put in some sweet potatoes. I don't have any studies to quote, but I cannot imagine bone broth being a problem in fighting CAC and high LDL-P. There are a lot of people on the internet claiming bone broth to be a miracle food, but the well-designed clinical ...

This is a huge study that was generally well designed. The main caveat is one they include in the Conclusions: In the context of an overall DASH-type diet , using glycemic index to select specific foods may not improve cardiovascular risk factors or insulin resistance. I would not give much weight o...

For a sweeter use of avocado, try chocolate avocado pudding: http://theprettybee.com/2014/01/chocolate-avocado-pudding-paleo-vegan.html I've been making something close to this for a long time. I tend to sweeten it with stevia and include some whey or (chocolate-flavored) beef protein powder which c...

The Discussion from that paper: In this study enroling 521 elderly individuals, we found a significant inverse relationship between TL and adiposity indices using both initial and follow-up data. TL measured at baseline and changes in TL during follow-up were significantly inversely associated with ...

The full text link to the paper:http://www.sciencedirect.com/science/ar ... 9706028634

I'm confused. Why would one want to increase GABA in the brain if worried about AD and cognitive impairment? The benzodiazepine class of drugs are classic GABA agonists (e.g. valium, librium, xanax). They clearly have adverse cognitive effects, so I am at a loss for why we would consider seeking sup...