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COMT rs4680 and Placebo Response

Alzheimer's, cardiovascular, and other chronic diseases; biomarkers, lifestyle, supplements, drugs, and health care.
Matisse
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COMT rs4680 and Placebo Response

Postby Matisse » Wed Apr 29, 2015 12:17 pm

From a new study:

"Patients homozygous for the rs4680 low-activity met allele (met/met), known to have high levels of dopamine, had the greatest placebo response. The high-activity val allele homozygous (val/val) patients had the lowest placebo response."

Met/met is AA. Val/val is GG.

Here's a link to the article.

http://www.cell.com/trends/molecular-me ... 71-4914(15)00043-X

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