Check out our new podcast

User avatar
DebbieG
Contributor
Contributor
Posts: 55
Joined: Fri Oct 13, 2017 8:19 am

Re: Check out our new podcast

Postby DebbieG » Fri Apr 17, 2020 5:25 pm

floramaria wrote:And in the podcast, he commented on people who have high HDL cholesterol and low triglycerides probably having good plasminogen levels.
Do those plasmologens not get to the brain?
From the excellent show notes :
34:38 Dr G – Plasmalogens are made in the peroxisomes of our body. If you have high HDL and low triglyceride levels, that’s usually an indicator of good plasmalogen levels. The plasmalogens are transported on HDL particles in the body. There’s a correlation, those with high plasmalogens have high HDL.


He also said "The essential fatty acids, DHA and EPA, act as peroxisome stimulators". As I think I understand it (sort of, incompletely), plasmalogens are created by the peroxisomes and transported to the brain via HDL under normal conditions. Through diet and supplementation with DHA and EPA, we stimulate the peroxisomes to make plasmalogens, as opposed to sending plasmalogens in any significant amounts to the brain intact from a dietary source. And APOE4s need higher levels of plasmalogens to start with, but our poor cholesterol transport makes cells get stiffer over time and peroxisome plasmalogen production degrades as this happens.

User avatar
Julie G
Mod
Mod
Posts: 8785
Joined: Sat Oct 26, 2013 6:36 pm

Re: Check out our new podcast

Postby Julie G » Thu Aug 19, 2021 7:05 am

Hi all! Check out our latest podcast, a continuation of my earlier discussion with Dayan Goodenowe, PhD, about plasmalogens as they relate to cognition for ApoE4 carriers specifically. Dr. Goodenowe also shares the results from his clinical trial that he recently presented at the AAIC. It was a fascinating conversation; I highly encourage everyone to take a listen. You can access the podcast here:

Dayan Goodenowe, PhD: Plasmalogens & Neurological Health (Part 2)

User avatar
nerdymel23
Contributor
Contributor
Posts: 98
Joined: Wed Feb 17, 2021 11:08 am
Contact:

Re: Check out our new podcast

Postby nerdymel23 » Sat Aug 28, 2021 2:12 pm

Julie G wrote:Hi all! Check out our latest podcast, a continuation of my earlier discussion with Dayan Goodenowe, PhD, about plasmalogens as they relate to cognition for ApoE4 carriers specifically. Dr. Goodenowe also shares the results from his clinical trial that he recently presented at the AAIC. It was a fascinating conversation; I highly encourage everyone to take a listen. You can access the podcast here:

Dayan Goodenowe, PhD: Plasmalogens & Neurological Health (Part 2)


I'm super intrigued with all of this! Thank you for the wonderful information.
ApoE3/4
Board Certified Functional Medicine Health Coach
Certified Wahls Protocol Health Coach
Certified ReCODE Health Coach

User avatar
Julie G
Mod
Mod
Posts: 8785
Joined: Sat Oct 26, 2013 6:36 pm

Re: Check out our new podcast

Postby Julie G » Mon Sep 06, 2021 2:37 pm

We've got a new podcast up. I recently had an interesting conversation with Sharon Hausman-Cohen, MD, the co-founder of IntellxxDNA. She’s put together a genomics tool that provides detailed actionable information. I’ve seen many with complex chronic health issues learn game-changing information from this test that helps them fine-tune their protocols with dramatic results. I’ve agreed to do my genomics and will share what I learn in part two. Check out the podcast (with transcript and show notes) here: Dr. Sharon Hausman-Cohen: Personalized Medicine Through Genomics

Blissful1
Contributor
Contributor
Posts: 16
Joined: Thu Nov 29, 2018 1:36 pm

Re: Check out our new podcast

Postby Blissful1 » Sat Sep 11, 2021 11:50 am

Julie G thank you for supplying so many great podcasts and this forum.
I listened to this podcast and I appreciate the idea that they look at many SNPs and how they interact so we can get more personalized suggestions. My question is do you know how this compares to sending our raw data from 23andme through genetic genie or one of the other programs that could look at our many SNPs and how to prioritize the info.
Also does this IntellxxDNA need to get a new saliva sample or can it take raw data from23andme ?
I went down the MTHFR rabbit hole (before we learned that many other SNPs modify or help this SNP) also for APOE4 - be great to know which of the many Bredesen 37 holes need to focused on personally.
You are appreciated

User avatar
Julie G
Mod
Mod
Posts: 8785
Joined: Sat Oct 26, 2013 6:36 pm

Re: Check out our new podcast

Postby Julie G » Sun Sep 12, 2021 1:13 pm

Julie G thank you for supplying so many great podcasts and this forum.
I listened to this podcast and I appreciate the idea that they look at many SNPs and how they interact so we can get more personalized suggestions. My question is do you know how this compares to sending our raw data from 23andme through genetic genie or one of the other programs that could look at our many SNPs and how to prioritize the info.
Also does this IntellxxDNA need to get a new saliva sample or can it take raw data from23andme ?
I went down the MTHFR rabbit hole (before we learned that many other SNPs modify or help this SNP) also for APOE4 - be great to know which of the many Bredesen 37 holes need to focused on personally.
You are appreciated

Great questions! This actually differs quite a bit from Genetic Genie and other similar programs. They identify issues, with either color coding or other prioritization codes but don't tell you the specific epigenetic actions you can take to intervene. My guess is that this will require a new saliva sample. I'll share more as I go through the process. FWIW, the downside to IntellxxDNA is the high price and the fact that it requires a practitioner visit to get results. That said, it's a one time test that could potential identify rate limiting steps to health optimization and Dr. Hausman-Cohen has very generously agreed to waive the fee for our current physicians to take her training so we can keep the same team. I reached out to Dr. Sunjya Schweig at the California Institute for Functional medicine, my practitioner, and he agreed to order my report, take the training, and guide me through this process. Dr. Hausman-Cohen also covers each practitioners first three reports so we additionally will have her expertise. I'm very curious to see what I will learn and will share it in a follow-up podcast.


Return to “Announcements and Events”

Who is online

Users browsing this forum: No registered users and 2 guests