ApoE4.Info

It's been interesting to follow your research trail over the past decade. For a while, many of your papers seemed to conclude a positive outcome with a HFLC diet. Recently, your publications seem to have drawn back on that a bit. I'd love to learn your current thoughts on that...especially on how it may overlap with E4 pathology.

I've read that you're a proponent of ion mobility testing. I'd love to learn more about that.

Also, in your opinion, what additional tests are best for assessing or quantifying CAD/CVD risk?

With his research on genetic variability of CVD treatments, would he recommend statins for E4 carriers? If it depends on other genetic variants, which ones should we look at carefully before deciding?

I previously submitted the questions in the quote at the bottom below.

New question here:

Despite 5.5 months of eating a diet of mostly fish and shellfish, lots of vegetables, avocados, some nuts, olive oil and almost zero saturated fat (very occasional grass fed meat, very little low-fat yogurt, no alcohol, no grains except very occasional white rice, no sugar …) while at the same time increasing my exercise level to 30 minutes a minimum of 3 times per week my LDL-P has stayed at about 2000 (measured at the beginning, 2.5 month mark and 4.5 month mark.) I have lost 25 pounds since my diet change.

I am both a hyper-absorber and a hyper-synthesizer of cholesterol per Boston Diagnostics testing.
Just fyi prior to changing diet my CT calcium heart scan score had doubled in one year's time placing me at the 85th percentile.

What types of recommendations (statins, ezetimibe, and otherwise) does Dr. Krauss generally make for APOE4s in particular with this type of profile?
If Dr. Krauss recommends statins what does he consider with regard to them contributing to the risk of dementia for E4s?

Here are my previous questions:

What diet does he recommend for apoe4s?

What diet does he recommend for apoe4s with high LDL-P?

Would he make any changes in those diet recommendations if the apoe4 person were a hyper synthesizer AND hyperabsorber of cholesterol?