2016 Meet-Up

[Gilgamesh]

Would love to be there, just looked at flights and cheapest was just under £1000 I will have to have a long think on that one!

I'd be coming from Europe, too, and the price of the long flight hurts. (August is the most expensive time to cross the Atlantic. Right now, roundtrip Continent-Boston flights, for ex., are only $440 for the spring; not so August....) I would really, really, really love to meet everyone, so I'm going to try to make it work somehow. We'll see.

[Kit]

I will absolutely be there. Can't wait. I am lucky I live only about 1000 miles from Colorado. Thanks for putting this together!

Kit

[Tincup]

I am lucky I live only about 60 or so miles from Chicago.

Kit, I believe the gathering is now in Boulder, CO at the AHS-16.http://www.ancestralhealth.org/blog-ent ... 11-13-2016

[Kit]

Okay, that pesky old dementia is at it again. So I corrected the post. Heck, I am only 1000 miles from Colorado, I will still be there!

[TheBrain]

I'll be there! I lived in the foothills west of Denver for 13 years, and I love Boulder. I'll probably stay a few days longer to visit with friends.

I'll want to do that EBT scan, as I've taken a lot of calcium supplements over the years, and my GYN wants me to take 1500 mg because I have osteoporosis. (Stavia, I'll have to look at those abstracts you posted about those New Zealand studies on calcium.)

Julie, great job getting Drs. David Raichlen, Steven Gundry, and Dale Bredesen to submit proposals! I hope all of them are accepted.

[circular]

A while back I had a notion that Drs. Bredesen, Gundry and Theoharides would make a great trifecta, although I'm not aware of Dr. Theoharides focusing on E4 [Update below …] or having an evolutionary slant, so he may not be spot on for the AHS, but general perspective is easily integrated into his work due to the contribution of modern lifestyles to stress and the flavanol poor diets (he was on the forefront of if not the founder of flavanol research). He was founder of Tuft's pharmacology division (pharmacology specialization would be very important in the context of our complex protocols), is very involved with brain inflammation issues and has the humanitarian spirit. While his focus in recent years has been largely on autism (for which he's apparently experiencing an acute funding crunch that may put an end to that research), he's drawn parallels between autism and AD in the context of inflammation. Maybe if he joined forces with the AD crowd he could end up helping with autism through the back door. The supplement that his pilot studies show address brain inflammation in autism and result in improvements in autism patients might be studied instead in the context of Alzheimer's. The trifecta would include a specialist in each of neurology, cardiology and immunology/pharmacology.

'Theoharis Theoharides, MD, PhD: Professor of Integrative Physiology & Pathobiology'

Research Synopsis
Our laboratory investigates the mechanism of selective secretion of cytokines and other pro-inflammatory molecules from mast cells. We have shown for the first time that mast cells can be activated by corticotropin-releasing hormone (CRH), the first molecule generated under stress, and by interleukin-1. CRH-activated mast cells lead to disruption of the gut-blood-brain barriers and thus contribute to brain inflammation. This process may participate in the pathophysiology of many diseases that worsen or precipitate under stress.

http://sackler.tufts.edu/Faculty-and-Re ... es-Profile

'Autism and brain immunity storms'

He received all his degrees from Yale University from where he was awarded the “Dean’s Research Award” and the “Winternitz Price in Pathology.” He trained in internal medicine at the New England Medical Center from which he received the “Oliver Smith Award “recognizing excellence, compassion and service.” He also received a Certificate in Global Leadership from the Fletcher School of Law and Diplomacy at Tufts University, and a J.F. Kennedy Fellowship at the Harvard Kennedy School of Government.
He is a member of 4 Academies and 17 scientific societies. He has published over 350 peer-reviewed research papers and 3 textbooks, with 17,500 citations. He has been placed in the top 1% of authors most cited in pharmacological and immunological journals. Dr. Theoharides was the first [?] to show that certain immune cells, called mast cells and known because they cause allergic reactions, can be stimulated by non-allergic triggers, such as stress hormones, to secrete inflammatory mediators leading to neuro-inflammation. He was also the first to show that stimulated mast cells secrete mitochondrial components outside the cells where they are mistaken by the body as “innate pathogens” and lead to inflammation that may explain auto-immune diseases. Based on these discoveries, Dr. Theoharides proposed the novel concept that mast cells play a critical role in brain inflammation, especially in Alzheimer’s disease, autism, chronic fatigue syndrome, fibromyalgia, migraines, multiple sclerosis and psoriasis, all of which worsen with stress. He has been awarded 17 patents and 23 trademarks. He also developed the dietary supplements [he doesn't personally benefit from these but since he's having a funding crunch they can now be purchased such that all proceeds go toward his research] ArthroSoft®, BrainGain®, CystoProtek®, FibroProtek®, MastoStop®, and NeuroProtek®. The latter was recently shown in two pilot clinical trials to significantly improve sociability in over 70% of children with autism in 6 months. [How 'bout testing that in Alzheimer's?] In order to bring these discoveries to the patients, he developed two nonprofit organizations, shown above. For his efforts, he was made “Archon” of the Greek Patriarchate, the highest honor bestowed by the Greek Orthodox Church, was inducted into the “Rare Disease Hall of Fame,” was given an “Honorary Doctor of Medicine” from Athens University, Greece, was made a Fellow of the American Academy of Allergy, Asthma, Immunology, and the European Academy of Allergology and Immunology, and was nominated to the American Academy of Arts and Sciences.]

http://www.autismone.org/content/autism ... ity-storms

Update:

I googled Theoharides and E4 and he was involved with this paper:

'Stress-induced interleukin-6 release in mice is mast cell-dependent and more pronounced in Apolipoprotein E knockout mice'

http://mastcellmaster.com/documents/Car ... ardRes.pdf

[Julie G]

Circ, I'm a huge fan of Dr. Theoharides because of the mast cell/neurodegenration connection. I suspect that we're on the infancy of learning about that overlap. Like you, I'm not sure he's a great fit for the AHS event, but please feel free to invite him if you'd like. OR, perhaps we could invite him to be a guest researcher/clinician on the site like we did with Dr. Dayspring? So many of us also deal with mast cell issues. It would be great to get his perspective.

Kit, my bad. This thread has meandered from Chicago to LA to Boulder. Your confusion prompted me to create a new dedicated thread with the most current information on our 2016 meet-up.

[Tiramisu1984]

Julie, I am also interested in attending. How would i sign up for the EBT heart scan? If i missed he thread, my apologies.

[Tincup]

Julie, I am also interested in attending. How would i sign up for the EBT heart scan? If i missed he thread, my apologies.

Email Lindsay at heartscan@comcast.net from http://www.frontrangepreventiveimaging.com/. She has blocked out the day before (Aug 10) for our group.

{Edit} Just confirmed with Lindsay that the cash price is $195.

[LG1]

Thanks for putting this together! I'm very interested in attending. Do we know how many of us are confirmed so far?

Laura