I'm in the small group and Gundry likes our Omega 3 index high. Mine was a bit high at 17.9 in Nov. I can tell when I'm taking a little too much (from all sources) as the bruising on my arms (they take a lot of abuse from workouts & rock climbing) look like someone on a high dose of warfarin (blood thinner) . I back off then.
I agree that bruising is a very good sign that omega-3s are too high. FWIW, Dr. Bredesen agrees with Dr. Gundry that E4 carriers need higher levels of omega-3s. For E4s, he recommends ≥10% on the omega-3 Index, but he worries about getting blood too thin. For instance, in the new book, he recommends an omega-6 to omega-3 ratio goal between 1:1 to 4:1 with the caution that <0.5:1 may be associated with bleeding disorders. Additionally, Dr. Bredesen continues to worry about 4/4 men in particular, especially those with a family history of hemorrhagic stroke, taking too much —or indeed ANY— fish oil. He recommends that those who fall into this small subset get an MRI with a microhemorrhage sequence (MP-RAGE) to determine whether any indication of early, unrecognized bleeding has occurred which is likely a sign ofcerebral amyloid angiopathy (CAA). He's finding early signs of CAA in healthy, cognitively normal, 4/4 men. For this group, he recommends zero fish oil, but plenty of actual fish to achieve the omega-3 index goal.
I also need Julie to give me voice lessons.
Ha, I know I sound like a dork. I'm working very hard to get over myself and focus on getting good info out there. That's the beauty of a community podcast. Any of us can host.