Biogen's promising Alzheimer's drug advances to Phase 3 trial
Posted: Sun Apr 26, 2015 10:43 am
To recap, Phase 1 included 166 patients with mild Alzheimer's symptoms. Those taking the higher doses had a small, but statistically significant improvement in cognition (using two assesments) compared to placebo. Even more encouraging; the longer patients were on the med, the greater the difference in cognition between the two groups. This is the first time an anti-amyloid agent improved cognition.
Unfortunately for us, E4 carriers were more likely to develop side effects that prohibited them from taking the higher doses
Still an important and exciting trial that MAY bode well for all of Banner's anti-amyloid trials. I'll be paying close attention to all. http://www.wsj.com/articles/biogen-deta ... 1426844101