Harrison wrote:Just wanted to clarify that the original Mercola article is talking about TDP-43, which is detected in 25-50% of Alzheimer's cases, but is more associated with other disease such as ALS or FTD. There is a case study of TDP-43 pathology being exacerbated by apoE4. The link to the Washington University report is talking about tau, which leads to the neurofibrillary tangles in AD. There is a theory of tau seeding, where it spreads from neuron to neuron in a prion-like way. ApoE4 is thought to increase tau phosphorylation, leading to tangles.
I think the evidence for foodborne aspects of this is remote, but you never know.
Harrison wrote:You're welcome. No kidding about so many facts and so little time. I sometimes feel like if one person (or perhaps an AI like IBM's Watson) could read every PubMed paper we would understand everything.
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