CSF Ferritin predicts cognitive decline in E4s

[Orangeblossom]

Do you feel OK Circular? I felt quite faint when my irons stores were very low, even though it didn't show anaemia.

[circular]

Do you feel OK Circular? I felt quite faint when my irons stores were very low, even though it didn't show anaemia.

I don't feel faint, but I'm definitely not yet as energetic as I feel I should be. I was really getting there until a freighterload of stress hit, so I'm sure that's affecting me. I suspect my ferritin, iron etc is okay, so I'm just running the iron panel to cross it off the list and not look back for a long time. I'm getting close to needing only a few labs a year to monitor what hasn't been optimal. Even if the iron panel is normal, if iron is low normal I may experiment to see whether a little bump up has noticeably beneficial effects on my energy. Would take at least a two round trial to confirm any bounce is the extra iron. I'll try to do it with diet.

[Orangeblossom]

Do you feel OK Circular? I felt quite faint when my irons stores were very low, even though it didn't show anaemia.

I don't feel faint, but I'm definitely not yet as energetic as I feel I should be. I was really getting there until a freighterload of stress hit, so I'm sure that's affecting me. I suspect my ferritin, iron etc is okay, so I'm just running the iron panel to cross it off the list and not look back for a long time. I'm getting close to needing only a few labs a year to monitor what hasn't been optimal. Even if the iron panel is normal, if iron is low normal I may experiment to see whether a little bump up has noticeably beneficial effects on my energy. Would take at least a two round trial to confirm any bounce is the extra iron. I'll try to do it with diet.

Sounds like a good plan.

[circular]

Okay ferritin/iron experts, I don't think there's anything too concerning here in the big picture. I notice my ferritin is lower this time than last, when it was 34.

TIBC 287 ug/dL (250-450)
UIBC 215 ug/dL (131-425)
Iron 72 ug/dL (27-159)
Iron Saturation 25% (15-55)
Ferritin 27 ng/mL (15-150)

Everything within the lab's normal ranges, but not simon01's target areas for ferritin and iron saturation. I notice Dr. Bredesen doesn't include these among his labs, at least not as discussed in his book. I would be a little worried that increasing iron would cause my iron itself to go too high.

I need to listen to Chris Masterjohn's podcast on this a second time.

[Stavia]

Circ, I would read your iron panel as normal

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[circular]

Thanks Stavia! That's what I expected and thought. Yea, one less thing to think about!

[simonh01]

You're borderline iron deficient, I wouldn't stress about it but you are definitely below the ranges I would be happy with.

[Lucy5]

simon wrote: You're borderline iron deficient, I wouldn't stress about it but you are definitely below the ranges I would be happy with.

simon, I'm curious if there's a specific lab result in circ's panel that you find concerning?

[simonh01]

simon wrote: You're borderline iron deficient, I wouldn't stress about it but you are definitely below the ranges I would be happy with.

simon, I'm curious if there's a specific lab result in circ's panel that you find concerning?

Iron Sat < 30%
Also the Ferritin of 27 is low I would want it over 50.

TIBC and UIBC are reversed so the lower the number the closer to iron overload, they look ok but are on the lower end

TIBC (Total Iron Binding Capactiy) > 250 if below 250 then potential iron overload
UIBC (Unsaturated Iron Binding Capacity > 150 if below 150 then potential iron overload

Again I probably wouldn't put this in the deficient or amenic category but on a scale you are definitely heading in that direction and I would work on correcting it.

[circular]

How much do these measurements fluctuate day to day? And how long could it take to go from borderline to being anemic? I'm thinking I could hold off per Stavia, retest in six months or so, and if there's a worsening from Simon's perspective then address it after seeing the trend.

At the same time, while my energy is improved, I wouldn't say my stamina is great. I couldn't say, work a full time job and carry on all of life's other duties without a real struggle. (Actually as a caretaker that's what's happening now, I just don't get paid.) But that could just be due to stress overload at this point.