Hi Dave,Heterozygote Dave wrote:This is follow up to my Oct 23 2020 post : I am 60 year old APOE 3/4 Hetero-zygote (previously?) with Alzheimer's taking Homotaurine (HT)...I researched the ALZ-801 case today and see they are off to more testing groups in second quarter of 2021 and that they identified a new brain chemical apparently brought forth by the HT.
I wish everyone the life saving positive outcome I have experienced.
Thanks for posting your great results with homotaurine. Since you mentioned ALZ-801, I thought I'd share the link from our new wiki ApoE4 Research: Why and How You Can Accelerate Alzheimer's Research for ApoE4 Carriers.
Biomarker Effects of ALZ-801 in APOE4 Carriers With Early Alzheimer's Disease is a Phase 2 clinical trial of ALZ-801 with primary outcomes focused on safety and secondary outcomes measured by 5 assessment of verbal, visual-spatial, memory and daily living skills. The locations are in the Czech Republic and the Nethlerlands:
According to Alzheon's website, if they achieve "promising biomarker results" they will file a "supplemental new drug application" to start a "Prevention Study in Asymptomatic ApoE 4/4s. Alzheon
Although they project this happening in late 2021, it seems likely it would be sometime in 2022. Looks like you're getting an early start on the research!