Other AD Risk Genes Found (listed)

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CoachDD
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Other AD Risk Genes Found (listed)

Post by CoachDD »

Interesting article from the National Institute of Aging regarding other genes that may factor into AD:

"Findings showed that after APOE4, the gene with the strongest association with amyloid deposits was ABCA7, especially in the asymptomatic and early symptomatic disease stages. Studies have previously connected ABCA7 with Alzheimer’s disease processes in the brain; these findings provide further evidence of its role. Research has also shown that African Americans are more likely than whites to have a variant of the ABCA7 gene, with almost double the risk of developing Alzheimer’s.

Other Alzheimer’s disease risk genes found to be associated with amyloid buildup at different disease stages included FERMT2, which was most pronounced in people with mild cognitive impairment; SORL1 and EPHA1, which were associated with both the mild cognitive impairment and dementia stages; and CLU, DSG2, and ZCWPWI, which were linked to the dementia stage. Results suggest genetic variants might affect Alzheimer’s disease processes differently across disease stages."

Here is the link: https://www.nia.nih.gov/news/genetic-ri ... es-disease
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J11
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Re: Other AD Risk Genes Found (listed)

Post by J11 »

Thank you CoachDD!

Any idea what the genes in this article might be?
https://www.sciencedaily.com/releases/2 ... 113223.htm
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