'dentification of dietary phosphatidylcholine metabolites as markers for increased CVD risk
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086762/
'dentification of dietary phosphatidylcholine metabolites as markers for increased CVD risk
Highlights
•One-carbon metabolism and the APOEε4 allele variant could interact in dementia.
•This potential interaction has not been addressed in prognostic dementia studies.
•We measured metabolites in sera in a longitudinal study on cognition in dementia.
•Choline oxidation metabolites seem to improve cognitive prognosis in APOEε4 carriers.
•In comparison, they may be detrimental to cognitive prognosis in non-carriers.
Interestingly however, our data suggests that higher concentrations of components of the choline oxidation pathway may be of benefit to patients with APOEε4, but potentially detrimental to patients without this allele.
Jafa wrote:I have assumed I am ApoE4 as I have a strong maternal family history of dementia...
Julie G wrote:Anybody else out there that beats 9? Please? Please someone make me feel better about my whacked methylation pathways...
No, sorry. You win, even from amongst the FaceBook crowd. Only one gal matched your requirement. At least we know that you come by your “methylation whisperer” title honestly.
sunrise wrote:Any suggestions for whose approach is gospel for APOE4 1 copy?
sunrise wrote:I have read Bredesen, gundry, hyman, perlmutter, lugavere and feel like my head is in a washing machine. Any suggestions for whose approach is gospel for APOE4 1 copy?
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