sunrise wrote:Any suggestions for whose approach is gospel for APOE4 1 copy?
Hi sunrise, and welcome. Since I'm the party of needing 9 eggs, let me make just a couple comments. I'm also a 3/4 and postmenopausal. I saw my lipids change quite a bit from my 40s, too.
First, I don't eat 9 eggs per day. Having numerous methylation variants, I supplement with 1000 mg of TMG (trimethylglycine) per day, to help reduce my body's need to rely on choline for creating methyl groups. At times I have also supplemented with phosphatidylcholine (PC), another way to reduce the need to use methyl groups to convert choline to PC. I also take methylfolate, b12 and small amounts of other B vitamins per day, again, to balance out how the body creates and uses methyl groups. If you want to know more about how this works, try the wiki post
https://wiki.apoe4.info/wiki/Methylation.
Now, as for diet, I quit using coconut oil and coconut milk and avoid fatty meats like bacon because they raise my ldl and total cholesterol way too high. I do still occasionally eat coconut yogurt and some baking with coconut flour because I eat dairy-free and low oxalate (which limits my choices for foods). I'm guessing you are eating a higher fat diet, and quite honestly, I've had to drop back the amount of fat to keep my numbers reasonable. I'm personally comfortable ATM with lipid numbers that slightly exceed the upper boundaries because my oxLDL and CRP (markers for inflammation) are very low, but I'm always looking for ways to drop those numbers.
That said, perhaps a good place to start is to look at your family health history. Do you have heart disease that runs in your family?
If so, that is a good place to start. It will be very important to reduce inflammation, especially if you eat foods that might uniquely cause you problems. You might also consider getting a coronary calcium scan to get a baseline of plaque.
If diabetes runs in your family, then I'd focus on your glucose tolerance.
And if you're like me, I have both in my family, so you have to find the fine line between too much fat and too much carb to get both set of numbers in line.
It takes some persistence, but keep trying, testing and adjusting, and do come back with any questions that pop up along the way.