"Scientists have long associated APOE4 with amyloid plaques, one of the two types of protein misfires in the brain that lead to development of Alzheimer’s and other dementias. But the connection with the other type of proteins — called tau tangles — has been more tenuous.
However, a new study published in JAMA Neurology has found that the link between APOE4 and dementia is even greater than originally believed."
Read the full article here: https://www.beingpatient.com/alzheimers-gene-apoe4/
Article: Alzheimer’s Gene APOE4 Tied to Tau Protein in the Brain
Re: Article: Alzheimer’s Gene APOE4 Tied to Tau Protein in the Brain
Hello LeciaB,LeciaB wrote:"Scientists have long associated APOE4 with amyloid plaques, one of the two types of protein misfires in the brain that lead to development of Alzheimer’s and other dementias. But the connection with the other type of proteins — called tau tangles — has been more tenuous.
However, a new study published in JAMA Neurology has found that the link between APOE4 and dementia is even greater than originally believed."
Read the full article here: https://www.beingpatient.com/alzheimers-gene-apoe4/
Welcome to the Forum and thank you for sharing the JAMA article regarding the link between ApoE4 and dementia.
We are so happy to have you participate with this supportive community.
Have you had an opportunity to explore the website?
The Primer is a great place to get started, it has a wealth of information and was written by the physician that started this forum.
You seem to have a strong science background and I thought you may also be interested to explore some additional information regarding the biochemistry of ApoE4 which can be found here.
The Wikki Page contains material regarding diet and lifestyle behaviors to support cognitive health, and much more!
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Again, we are happy you are here.
PJ
Think Positive Be Positive
Functional Medicine Certified Health Coach
Functional Medicine Certified Health Coach