giftsplash wrote:Concept I want to share with the group.
It seems that there is a genetic component to the CoronaVirus. Although it is too early to tell but people who catch the virus outside of China seem to be able to survive at a much higher rate. Better medical care might be one reason, but genetics might be another. People who carry the ACE2 receptor are more likely to be infected with the SARS-CoV
What jumped out at me is that if you look at the people who carry the ACE2 receptors it inversely correlated to regions of people carrying the APOE4 gene. Not sure if anyone ever seen a correlation study between ACE2 and APOE4. Or what to make of this.
https://onlinelibrary.wiley.com/doi/pdf ... .6340301.x
Yikes, indeed!Julie G wrote:I hope so. My husband is returning tomorrow from two back-to-back trips to South Korea where he interacted with other flight crew members who were within 14 days from having returned from China. Yesterday, I called my local health department to see where we could go to get tested should he (or I) show symptoms. I learned that my state has no test kits and that they don't want us seeking medical help until he has a fever and lower respiratory symptoms (cough & shortness of breath) severe enough to require hospitalization. Yikes
Julie G wrote:Yikes
aphorist wrote:First clinical trial for Coronavirus - 24 G IV infusion of Vitamin C
It's a very high amount, probably to prove efficacy. Normal IV's are like 10-15 grams. But, long story short if you have some vitamin C daily... even like 200 mg, it will likely help prevent coronavirus. 2 grams is the upper tolerable limit in adults, AFAIK.
giftsplash wrote:It seems that there is a genetic component to the CoronaVirus. Although it is too early to tell but people who catch the virus outside of China seem to be able to survive at a much higher rate. Better medical care might be one reason, but genetics might be another. People who carry the ACE2 receptor are more likely to be infected with the SARS-CoV
The study - a preprint that has not yet been peer-reviewed - is entitled Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov, By Yu Zhao et al., bioRxiv, 2020] and is authored by a group of medical scientists based at Tongji University in Shanghai
The authors explain that “2019-nCov was reported to share the same receptor, Angiotensin-converting enzyme 2 (ACE2)” as the SARS disease, an outbreak of which in 2003 seemed almost exclusively to kill Northeast Asians.
Based on “the public database and the state-of-the-art single-cell RNA-Seq technique” the Chinese scientists “analyzed the ACE2 RNA expression profile in the normal human lungs.” Crucially, they further found (in a comparison of eight individual samples) that the “Asian male one has an extremely large number of ACE2-expressing cells in the lung” in comparison to other races. (The database was based on analysis of eight normal human lung transplant donors of different races.)
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