Alpha-1 Antitrypsin helping brain inflammation

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FitFoodie
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Alpha-1 Antitrypsin helping brain inflammation

Postby FitFoodie » Wed Mar 11, 2020 1:53 pm

https://jneuroinflammation.biomedcentra ... 014-0165-8

a medication that already exists for people with this deficiency to help reduce their emphysema and liver disease could be useful in fighting AD.

I know from my lung issues that I carry one less-than-ideal version of the gene that causes alpha-1 antitrypsin deficiency. My combo is shared by 8% of the population and isn't considered pathogenic, though it does mean I make on average only 80% of normal of this substance that dampens inflammation.

Random side note, I also know from other research that the quantity of A-1AT a person produces during an immune system activation is also linked to their weight, with being underweight a bad thing.

Anyone who has done Promethease can look up their genes for this condition. My "less-than-ideal but still normal" gene situation doesn't qualify for the med...

circular
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Re: Alpha-1 Antitrypsin helping brain inflammation

Postby circular » Wed Mar 11, 2020 10:36 pm

Thanks, I am same as you. I once did the blood test and it came back normal. You might order that to look under the hood a bit.
ApoE 3/4 > Thanks in advance for any responses made to my posts.

Jafa
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Re: Alpha-1 Antitrypsin helping brain inflammation

Postby Jafa » Thu Mar 12, 2020 3:58 am

Me too

FitFoodie
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Re: Alpha-1 Antitrypsin helping brain inflammation

Postby FitFoodie » Fri Mar 13, 2020 5:11 pm

Jafa wrote:Me too
circular wrote:Thanks, I am same as you. I once did the blood test and it came back normal. You might order that to look under the hood a bit.


Probably should. My level was tested when I was sick. It was normal. The doctor said that being sick, it should probably be higher. End of discussion. I don't see that doctor anymore, but I also didn't follow up on the issue.


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