Young blood NOT necessary, a simple oil change will do

Insights and discussion from the cutting edge with reference to journal articles and other research papers.
User avatar
Julie G
Mod
Mod
Posts: 8534
Joined: Sat Oct 26, 2013 6:36 pm

Young blood NOT necessary, a simple oil change will do

Postby Julie G » Mon Jun 15, 2020 7:22 am

Researchers have essentially found a molecular “reset button” to reverse aging. A new study shows that diluting blood plasma rejuvenates tissue and reverses aging in mice. See the press release here. If this holds up in human trials, plasmapheresis (already FDA approved and in use) could prove to be a game changer for both prevention and possibly treatment of cognitive decline and all diseases associated with aging.

Lucy5
Support Team
Support Team
Posts: 480
Joined: Sat Oct 03, 2015 10:52 am
Location: Colorado

Re: Young blood NOT necessary, a simple oil change will do

Postby Lucy5 » Mon Jun 15, 2020 11:34 am

Fascinating Julie; definitely an area of research to keep an eye on!

Tincup
Mod
Mod
Posts: 2637
Joined: Fri Aug 08, 2014 2:57 pm
Location: Front Range, CO

Re: Young blood NOT necessary, a simple oil change will do

Postby Tincup » Mon Jun 15, 2020 3:04 pm

My mom had a lymphoma, Waldenstrom’s macroglobulinemia. Hyper blood viscosity can be a symptom and plasmapheresis was a commonly used treatment for it. Only reporting this to say it is readily available.

Wonder if plasma donation at the blood donation center would have any similar effect? Nothing going back in, your body would have to be making its own new stuff.
Tincup
E3,E4

User avatar
floramaria
Support Team
Support Team
Posts: 823
Joined: Tue Jul 04, 2017 11:22 am
Location: Northern New Mexico

Re: Young blood NOT necessary, a simple oil change will do

Postby floramaria » Mon Jun 15, 2020 3:52 pm

Tincup wrote:Wonder if plasma donation at the blood donation center would have any similar effect? Nothing going back in, your body would have to be making its own new stuff.

Interesting idea. Hopefully the researchers will think of that too, and test it.
Functional Medicine Certified Health Coach
IFM/ Bredesen Training in Reversing Cognitive Decline (March 2017)

User avatar
Julie G
Mod
Mod
Posts: 8534
Joined: Sat Oct 26, 2013 6:36 pm

Re: Young blood NOT necessary, a simple oil change will do

Postby Julie G » Mon Jun 15, 2020 4:14 pm

My mom had a lymphoma, Waldenstrom’s macroglobulinemia. Hyper blood viscosity can be a symptom and plasmapheresis was a commonly used treatment for it. Only reporting this to say it is readily available.

Leading me to wonder if plasmapheresis could also overcome the fibrinogen/hypercoagulation uncovered by Gladstone???

Tincup
Mod
Mod
Posts: 2637
Joined: Fri Aug 08, 2014 2:57 pm
Location: Front Range, CO

Re: Young blood NOT necessary, a simple oil change will do

Postby Tincup » Mon Jun 15, 2020 5:18 pm

Julie G wrote:Leading me to wonder if plasmapheresis could also overcome the fibrinogen/hypercoagulation uncovered by Gladstone???

In the case of Waldenstrom's, if a person has this hypercoagulation symptom, plasmapheresis was done fairly frequently, like every two weeks. Not sure how soon the Gladstone hypercoagulation would reappear.
Tincup
E3,E4

User avatar
Julie G
Mod
Mod
Posts: 8534
Joined: Sat Oct 26, 2013 6:36 pm

Re: Young blood NOT necessary, a simple oil change will do

Postby Julie G » Tue Jun 16, 2020 10:58 am

In the case of Waldenstrom's, if a person has this hypercoagulation symptom, plasmapheresis was done fairly frequently, like every two weeks. Not sure how soon the Gladstone hypercoagulation would reappear.

I'm unsure how often plasmapheresis would have to be repeated. I know that kidney dialysis is typically done three times per week and fully covered by insurance. If this research holds up in humans, it will be hard not to justify it.

User avatar
Nords
Senior Contributor
Senior Contributor
Posts: 89
Joined: Sat Nov 02, 2013 8:55 pm
Location: Oahu.
Contact:

Re: Young blood NOT necessary, a simple oil change will do

Postby Nords » Sat Jun 20, 2020 5:44 pm

Julie G wrote:Researchers have essentially found a molecular “reset button” to reverse aging. A new study shows that diluting blood plasma rejuvenates tissue and reverses aging in mice.

Every time I read about mice studies, I can't help but reflect on how we're improving the lifespan... of mice.

I sure hope even a tiny fraction of this rodent research eventually crosses over to humans.

Tincup wrote:My mom had a lymphoma, Waldenstrom’s macroglobulinemia. Hyper blood viscosity can be a symptom and plasmapheresis was a commonly used treatment for it.

In 2011 when my father had emergency surgery for a perforated ulcer, he went to a skilled nursing facility to recover. It was also clear that he could no longer live independently with mid-stage Alzheimer's, and the SNF had a care facility wing, so he moved into it.

About two weeks later one of the staff nurses spotted symptoms which were soon diagnosed as Waldenstrom’s macroglobulinemia. The treatment was chemotherapy and possibly plasmapheresis (I don't remember hearing about the latter). Because of all the substances Dad was getting plugged into, the oncologist installed a subcutaneous port below his left collarbone.

With Alzheimer's, I can't tell you how many times my father rediscovered that port for the first time all over again just about every morning. It fed directly into all of his lifelong conspiracy theories about doctors treating him as a lab rat.
Author of "The Military Guide to Financial Independence and Retirement". Royalties are donated to military charities.
Spring 2020: "Raising Your Money-Savvy Family For Next Generation FI."
I don't read every post- please send a PM.

Tincup
Mod
Mod
Posts: 2637
Joined: Fri Aug 08, 2014 2:57 pm
Location: Front Range, CO

Re: Young blood NOT necessary, a simple oil change will do

Postby Tincup » Sat Jun 20, 2020 5:54 pm

Nords wrote: Because of all the substances Dad was getting plugged into, the oncologist installed a subcutaneous port below his left collarbone.

With Alzheimer's, I can't tell you how many times my father rediscovered that port for the first time all over again just about every morning. It fed directly into all of his lifelong conspiracy theories about doctors treating him as a lab rat.


My mom broke her hip. At the hospital she needed a 24 hour aide to keep her from ripping out the IV's in her arm. She was very confused being in the hospital. This factored into my decision not to treat a respiratory infection 10 months later (which would have required a hospital visit and IV antibiotics). I decided she didn't need another hospital visit. Before she was very demented, she'd told me in no uncertain terms, "if I can't be effective, I don't want to be here." The respirator infection ended up being her last illness, which I suspected would be the case when I make the decision. It was a difficult decision, but I had the support of her doc & the rest of the family (I'm an only child, so the final decision was mine).
Tincup
E3,E4


Return to “Science and Research”

Who is online

Users browsing this forum: No registered users and 18 guests