I have been otherwise preoccupied as of late, but this seemed like just the kind of research needed to support the notion of Alzheimer's Prevention. This is just the abstract, I'll see if I can find the whole study.
Findings from 2 longitudinal studies
Results During a median follow-up of 5.8 years in CHAP and 6.0 years in MAP, 379 and 229 participants, respectively, had incident Alzheimer dementia. In multivariable-adjusted models, the pooled HR (95% CI) of Alzheimer dementia across 2 cohorts was 0.73 (95% CI 0.66–0.80) per each additional healthy lifestyle factor. Compared to participants with 0 to 1 healthy lifestyle factor, the risk of Alzheimer dementia was 37% lower (pooled HR 0.63, 95% CI 0.47–0.84) in those with 2 to 3 healthy lifestyle factors and 60% lower (pooled HR 0.40, 95% CI 0.28–0.56) in those with 4 to 5 healthy lifestyle factors.
Conclusion A healthy lifestyle as a composite score is associated with a substantially lower risk of Alzheimer's dementia.
https://n.neurology.org/content/early/2 ... 0000009816
Edit - Here is a much better discussion
https://www.nih.gov/news-events/news-re ... lzheimer's.