Wine and Cheese Might Actually Help You Avoid Dementia

[NewRon]

https://mymodernmet.com/wine-cheese-dementia-study/

[TheresaB]

Seems as though those are two things ApoE4s should avoid. Did the research stratify by ApoE status?

[BrianR]

Genetic Factors of Alzheimer’s Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study

Behind a paywall, you'll need to use Sci-hub to look at it.

The study used retrospective food consumption questionnaires. Which, of course, are known to have issues.

APOE4 status was considered. E.g.:

Predictors of fluid intelligence by APOE4 status.png

They claim to have accounted for social-economic stratification, but didn't provide any data stratified by that factor. (Wealth or income can influence both wine & cheese consumption and dementia outcomes.) Also, I wonder if wine & cheese are more often consumed in the company of others, which I expect would improve dementia outcomes.

Overall, I just can't get very excited over results based on food questionnaires. I wouldn't be surprised if modest wine and cheese consumption, particularly in the context of meals consumed socially, would not be harmful for APOE4+. I could believe that additional non-carbohydrate calories consumed by non-obese seniors might improve outcomes.

[Nikki2019]

I just stumbled across this notion in yahoo news as I was scrolling to read about the latest with the Covid situation. It surprised me, because I have heard Gundry say to stay away from E4's favorite food, cheese. So I looked in this forum and see it has already been spoken for.

When I think of wine and cheese, I think of socializing with intellectuals over a game of chess. As opposed to chugging a beer at a frat party with a bunch of drunk bafoons.

To better understand if it is really the wine and cheese.. maybe bring that to the frat party and the beer to the chess game?
https://www.yahoo.com/lifestyle/wine-ch ... 00304.html