Wine and Cheese Might Actually Help You Avoid Dementia

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Wine and Cheese Might Actually Help You Avoid Dementia

Postby NewRon » Sat Dec 19, 2020 5:44 am

Apo E4/E4, Male, Age 56

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Re: Wine and Cheese Might Actually Help You Avoid Dementia

Postby TheresaB » Sat Dec 19, 2020 5:57 am

Seems as though those are two things ApoE4s should avoid. Did the research stratify by ApoE status?
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Re: Wine and Cheese Might Actually Help You Avoid Dementia

Postby BrianR » Sat Dec 19, 2020 7:55 am

Genetic Factors of Alzheimer’s Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study

Behind a paywall, you'll need to use Sci-hub to look at it.

The study used retrospective food consumption questionnaires. Which, of course, are known to have issues.

APOE4 status was considered. E.g.:
Predictors of fluid intelligence by APOE4 status.png

They claim to have accounted for social-economic stratification, but didn't provide any data stratified by that factor. (Wealth or income can influence both wine & cheese consumption and dementia outcomes.) Also, I wonder if wine & cheese are more often consumed in the company of others, which I expect would improve dementia outcomes.

Overall, I just can't get very excited over results based on food questionnaires. I wouldn't be surprised if modest wine and cheese consumption, particularly in the context of meals consumed socially, would not be harmful for APOE4+. I could believe that additional non-carbohydrate calories consumed by non-obese seniors might improve outcomes.
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Re: Wine and Cheese Might Actually Help You Avoid Dementia

Postby Nikki2019 » Sun Jan 03, 2021 2:44 pm

I just stumbled across this notion in yahoo news as I was scrolling to read about the latest with the Covid situation. It surprised me, because I have heard Gundry say to stay away from E4's favorite food, cheese. So I looked in this forum and see it has already been spoken for.

When I think of wine and cheese, I think of socializing with intellectuals over a game of chess. As opposed to chugging a beer at a frat party with a bunch of drunk bafoons. :lol:

To better understand if it is really the wine and cheese.. maybe bring that to the frat party and the beer to the chess game? ... 00304.html
As E4 s, we are inherent fighters and don't give up so easily.

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