Has anyone been following the field of genetic editing and CRISPR-Cas9? Given how protective ApoE 2/2 is I'm almost surprised that there are still no companies that offer genetic editing with a goal of substituting whatever ApoE SNPs one has to ApoE 2/2. Provided this could be done safely, this could be revolutionary. I understand that most diseases involve complex interactions of dozens of genes, but in the case of Alzheimer's even focusing on the single gene can seemingly be very impactful.
I'm curious what others think. When do you think the first preventive treatments like this will become available? I also wonder if they might become available in countries other than the US first. Are you aware of any companies already working on this?
CRISPR-Cas9 against ApoE4
Re: CRISPR-Cas9 against ApoE4
This is exciting!ApropoE4 wrote:https://clinicaltrials.gov/ct2/show/NCT03634007
It'd be great to see studies like this aimed at prevention too, not just treatment.
