Welcome to the forum vandalee. As another 3/4 who is on statins (rousuvastatin 10mg), be sure to add ubiquinol such as this
. Co-Q10 levels decrease with all statins. With your lifestyle changes and supplements, maybe you have already perused Stavia's primer. Oh, 20 hours---this must be the shock of the CAC score & E4 all at once. Have you had your vitamin D level checked?
I'm assuming that your doctor did not want to stress test you prior to starting running, but I would focus on time (jog/walk) rather than sprint as you gradually adapt. Many times athletes dismiss a "twinge" in the chest, unfortunately my husband being one of them. As noted in a recent post, the E4 allele does increase our risks of silent damage. I wear a Polar monitor for feedback especially noting a healthy brisk heart rate recovery. Always recommended to cross train with non-joint pounding sport, while you continue your weight loss.