I can't work out my APOE results

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TerryG
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I can't work out my APOE results

Postby TerryG » Fri Sep 01, 2017 8:39 pm

Hi, could someone please help me work out what my APOE result is - I've attached 2 screenshots from 23andMe raw data. Am I 3/4 or 2/4?

with thanks,
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Stavia
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Re: I can't work out my APOE results

Postby Stavia » Fri Sep 01, 2017 9:09 pm

hi Terry and welcome.
I can't work it out either.
You could unlock your health report on 23andme or run it through Promethease.

Unless another member knows?

Matisse
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Re: I can't work out my APOE results

Postby Matisse » Fri Sep 01, 2017 10:48 pm

It's 3/3. Look up GS246 on snpedia.

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Re: I can't work out my APOE results

Postby Lucy5 » Fri Sep 01, 2017 11:40 pm

Hi Terry and welcome to our site! I see Matisse has already pointed out your info indicates you're 3/3. Quote below is copied from SNPedia
Gs246

Gs246
Magnitude 2
Repute Good
Summary APOE E3/E3
Criteria Gs246/criteria

Apo-ε3/ε3, the most common form of APOE. It is considered the "neutral" genotype, with E2 having lower risk and E4 having higher risk of Alzheimer's disease. Criteria: rs429358(T;T), rs7412(C;C) .

TerryG
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Re: I can't work out my APOE results

Postby TerryG » Sat Sep 02, 2017 5:23 am

thanks Lucy5 and Matisse, that helps because I was really struggling to understand the formula for working out my version of APOE.

and thanks for welcome to the site - I'm loving the reading and the learning.

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sylvieJ
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Re: I can't work out my APOE results

Postby sylvieJ » Sat Sep 02, 2017 7:34 am

Hello Terry, and welcome to the forum.

We are happy that you have found this community. I suggest that you read over the PRIMER as it is filled with great information that you may find useful.
PRIMER

There are many experienced members in this community who have a wealth of knowledge and experience. I'm happy that one of your questions has already been answered. Please reach out and post your questions. We are all here to share and support.
Kind regards
Sylvie

TerryG
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Re: I can't work out my APOE results

Postby TerryG » Sat Sep 02, 2017 7:00 pm

Thanks Sylvie - I have been reading through the primer - it's helpful, but at times confusing as I slowly learn the lingo in this world. I'll keep posting my questions!

cheers,
Terry

TerryG
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Re: I can't work out my APOE results

Postby TerryG » Sun Sep 03, 2017 5:13 pm

One further question...

I seem to be a bit slow on the uptake - I don't understand how I am 3/3 with the result I have. - I've attached another screen shot of the Stirling app 'translation' of the 23andme raw data.

Is it by default as I'm -/- for both those snp's?

thank you, Terry

Screen Shot 2017-09-03 at 11.06.23 am.png
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Stavia
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Re: I can't work out my APOE results

Postby Stavia » Sun Sep 03, 2017 7:25 pm

TerryG wrote:One further question...

I seem to be a bit slow on the uptake - I don't understand how I am 3/3 with the result I have. - I've attached another screen shot of the Stirling app 'translation' of the 23andme raw data.

Is it by default as I'm -/- for both those snp's?

thank you, Terry

Screen Shot 2017-09-03 at 11.06.23 am.png



snpedia
https://www.snpedia.com/index.php/APOE

Capture.PNG
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Stavia
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Re: I can't work out my APOE results

Postby Stavia » Sun Sep 03, 2017 7:29 pm

Stavia wrote:
TerryG wrote:One further question...

I seem to be a bit slow on the uptake - I don't understand how I am 3/3 with the result I have. - I've attached another screen shot of the Stirling app 'translation' of the 23andme raw data.

Is it by default as I'm -/- for both those snp's?

thank you, Terry

Screen Shot 2017-09-03 at 11.06.23 am.png



snpedia
https://www.snpedia.com/index.php/APOE

Capture.PNG



https://www.snpedia.com/index.php/Gs246


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