I found this interesting and worth sharing:
"... A recent study using data from the Framingham Heart Study suggests that because men in middle age have a higher rate of death from cardiovascular disease than women in middle age, men who survive beyond age 65 may have a healthier cardiovascular risk profile and thus an apparent lower risk for dementia than women of the same age.{160} Epidemiologists call this “survival bias” because the men who survive to older ages and are included in studies tend to be the healthiest men; as a result, they may have a lower risk of developing Alzheimer’s and other dementia than the men who died at an earlier age from cardiovascular disease. More research is needed to support this finding...."
From 2017 ALZHEIMER’S DISEASE FACTS AND FIGURES
https://www.alz.org/documents_custom/20 ... igures.pdf
{160} Chene G, Beiser A, Au R, Preis SR, Wolf PA, Dufouil C, et al.
Gender and incidence of dementia in the Framingham Heart Study
from mid-adult life. Alzheimers Dement 2015;11(3):310-20.
Survival bias
Re: Survival bias
Makes sense. AD runs on my dad's side of the family and he lost a couple of cousins to heart attacks. My dad survived his heart attack in his early 60s, but went on to develop AD in his late 70s. But who knows if his cousins might have had the same fate getting AD had they survived their heart attacks.
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floramaria
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Re: Survival bias
Very Interesting. Thanks for the post, Tongass.
Functional Medicine Certified Health Coach
IFM/ Bredesen Training in Reversing Cognitive Decline (March 2017)
ReCODE 2.0 Health Coach with Apollo Health
IFM/ Bredesen Training in Reversing Cognitive Decline (March 2017)
ReCODE 2.0 Health Coach with Apollo Health
Re: Survival bias
Was just thinking about this. Makes sense.
Re: Survival bias
A health risk for men as they age:
"Dr. Forsberg of Uppsala University and his colleague Jan Dumanski have published a series of papers about the phenomenon called L.O.Y., or loss-of-Y, in which men’s blood and other cells mysteriously start shedding their Y chromosomes with age.
Smoking hastens the depletion of the Y chromosome in men’s blood cells, the researchers have found. Men with a high percentage of Y-free cells — 10 percent or more — are at a heightened risk of dying in the near future, compared with similarly aged men whose cells have hung onto their Y’s.
And men with Alzheimer’s disease are more likely to be L.O.Y. men than are their non-demented cohorts."
https://www.nytimes.com/2018/06/11/heal ... osome.html
"Dr. Forsberg of Uppsala University and his colleague Jan Dumanski have published a series of papers about the phenomenon called L.O.Y., or loss-of-Y, in which men’s blood and other cells mysteriously start shedding their Y chromosomes with age.
Smoking hastens the depletion of the Y chromosome in men’s blood cells, the researchers have found. Men with a high percentage of Y-free cells — 10 percent or more — are at a heightened risk of dying in the near future, compared with similarly aged men whose cells have hung onto their Y’s.
And men with Alzheimer’s disease are more likely to be L.O.Y. men than are their non-demented cohorts."
https://www.nytimes.com/2018/06/11/heal ... osome.html
