Since I started Dr. Bredesen’s protocol, I’ve been taking Life Extension’s NAD+ Cell Regenerator (NIAGEN nicotinamide riboside), 100 mg, per day. Is this along the lines of your suggestion that niacin might help? Or would it need to be the flushing niacin? I still have 250 mg of that form on hand. I could never tolerate any higher dose for my coronary artery disease, so I stopped it altogether. The random intense flushing, especially in the middle of the night and in social situations, was intolerable, even at 500 mg.
I checked out Robert Miller’s Facebook page, and all I saw were posts about Australian politics. Maybe if I follow him, I’ll see more of his posts?
The nicotinamide riboside should be accomplishing something similar, more of exogenous NAD+. The idea with the niacin is to convert some betahydroxybuterate (BOHB) to acetoacetate. The doseages talked about are much lower - like 35mg, so the flushing should be modest, I would think. No guarantee's, just thought it might be worth trying since you have high levels of BHOB.
My links to his page contain a search for Niacin and the second one has a search for niacin NAD+. These searches should focus the posts and avoid the political ones. Miller has been experimenting with this a lot.
Other thoughts would be to shift your eating window to start at sunrise, focussing protein then. Eating only during daylight. This is a circadian rhythm thing. Also try to get outside in the first hour of sun, exposing your naked eyes to the early morning sunlight (not meaning at all to stare at the sun). This is to get your leptin timing correct. Again getting some sun at midday. Idea is the body (and eyes) respond to the solar cues.