I made a similar post in the Getting Started forum, but figured an introduction would be more appropriate here. I take my health seriously and recently found out I have the APOE 3/4 combo, and I think it's important to know these things to prevent future ailments as much as possible.
It's confusing, however, since finding out I'm an E4 carrier, none of the associated conditions make sense. Here are my personal stats:
Age: 30
Sex: Male
Age: 30
Sex: Male
Weight: 165
Height: 6'
Body fat: 6-8%
LDL cholesterol (mg/dL): 51
HDL (mg/dL): 76
Triglycerides (mg/dL): 40
My diet consists of tons of saturated fat (red meat, butter, coconut oil, egg yolks, etc.). I do avoid processed grains and sugars, however. I also exercise often, almost every day.
Now here's where it's even more confusing; my entire family does not follow my healthy lifestyle but they are also in pristine health. My parents (in their 50s) consume copious amounts of beer and red meat, and both have low cholesterol and are extremely mentally sharp. Same with my grandparents (in their 70s). My great grandparents, before they died (at around 80-90), were mentally sharp and consumed soda and potato chips daily. We have a large family who live relatively unhealthy lifestyles, but no cases of Alzheimer's or high cholesterol. Also 23andMe proved that I do indeed share their DNA
.Has anyone else seen a situation such as this? I don't know which side (it could even be both) that the E4 is on, but it doesn't make sense either way.
Does anyone know of any other genes that combat the cholesterol/Alzheimer effects of E4?
Does anyone else have E4 and not struggle with cholesterol issues?
I thought this would provide some useful info, as much of the research and internet discussions I've seen seem to assert that APOE4 causes high cholesterol and Alzheimer's, but clearly there are other factors at play.
