I started reading on this site after discovering that a LCHF diet sent my cholesterol counts through the roof. My total was about 300 while my LDL was about 200. I went for NMR lipoprofile expecting that this would show my concerned Dr that all was well. Instead, my LDL-P was 2470. Ackkk!
Anyway, reading led me to wonder if perhaps I would turn out to be APOE4 positive. I am E3/E4 according to 23andme and Prometheas. In addition it seems I am het for the 1298 mthfr defect. Inspired by your stories here (as well as by Bredesen) I decided to ask for as many lab tests as I thought my skeptical Dr would agree to. Among other things I checked my B vitamin levels. I was kind of hoping that I would turn out to be low on B12 and that perhaps that would explain my lack of energy and motivation as well as occasional mental foggiest. Well, my B12 was fine (about 700 as I recall). However, the B6 was high. I think the upper limit on normal was about 47. Mine was 110. I was taking a multivitamin that included B6, but not a lot. Could this be the result of MTHFR related problems? Could the high B6 cause me problems (like fogginess or lack of motivation almost like depression not sad just not very productive at work)? If so, what can I do about it (other than stopping that multivitamin).