Conflicting Test Results
Posted: Sat Dec 29, 2018 11:35 am
Hi everyone, I recently did the 23andme and Ancestry DNA tests to find out about my background and genetic risk factors. When I opened my 23andme results, I was surprised to find out that I had one copy of the APOE4 gene. I dug into the raw data further and found out I'm an E3/E4 (SNP rs429358 = CT, SNP rs7412 = CC). However, my raw data from Ancestry seems to indicate that I'm an E3/E3 (SNP rs429358 = TT, SNP rs7412 = CC). Just to see if there were any other differences, I compared several other markers related to Alzheimers betwen the two data sets, yet those all matched.
Has anyone else experience a similar result? If so, did you request a re-test from either company? I paid over $100 extra to obtain the 23andme results, so I'm more inclined to believe that result. However, you'd think for a gene with such high stakes, there would be more consistency between different testing services.
Has anyone else experience a similar result? If so, did you request a re-test from either company? I paid over $100 extra to obtain the 23andme results, so I'm more inclined to believe that result. However, you'd think for a gene with such high stakes, there would be more consistency between different testing services.