Re: MTHFR and E4/E4
Posted: Mon Jan 07, 2019 3:13 pm
Torimintz wrote:THanks for the info on rs1133 . I am G/G on 23 and me
But, what about rs1131. I am T/T on 23ANDME, Is that the bad one?
It is all so confusing
As Its Me said, you are the "good one" here as well!
This is how you can "convert" your values in 23andme to SNPedia's:
Look up each gene of interest on SNPedia, do you see in the upper right where it says "orientation"?
If the orientation is plus, do nothing to your 23andme value. An "A" is an "A," a "G" is a "G" and so forth
If the orientation is minus, then switch whatever bases you see on 23andme to the opposite bases (also known as nucleotides):
A becomes T
T becomes A
C becomes G
G becomes C
So in your example, you had G/G on 23and me, but on SNPedia, it says "minus" so you convert the G's to C's. And for the other one, it's also minus, so your T/T becomes A/A.
Hope that helps. That's really it!
Would it be helpful if I made a Youtube video on hacking your raw data from 23andme? I've been wanting to!