whit4health wrote:Hi, I'm new to this forum. I've known for about a year that I have E4/E4 as well as MTHFR C677T. I've been reading and doing as much as I can to prevent issues. Neither of my parents had Alzheimer's and no one in their past history has. However, there was a massive stroke in both grandfathers at around age 75 and my dad died of a heart attack at 72. My mother lived to 86 without Alzheimers. She was not a healthy eater either. I will soon be 54 and I've been a pretty healthy eater and have exercised moderately since I was 24. I've noticed during certain times, my mind does not do as well, especially with changes during the monthly cycle. I'm 90% vegan, but I definitely cheat on my diet. Blood work looks good. I could definitely lower my LDL a bit more, but HDL is excellent. Finding all this out in the last year had depressed me initially, but I now feel that knowing helps me work on prevention even more. It also helps my children who are still in their late teens and early 20's to start their protocols early. My main question here, is does anyone else know if they have a MTHFR mutation as well as the E4/E4 and do you follow a certain diet/protocol that is slightly different from what I'm reading here. Seeing that I need to change my diet even more makes it difficult, ie removing all grains, certain vegetables I enjoy and other items does not make it easy. Certainly, I know my kids will never do this at this stage in their lives. Thanks for any advice.
Welcome to the site whit4health!
I am truly sorry for your losses!
Thank you for sharing your story with us.
I love to ready introductions from new members who, like YOU, take health into their own hands and even more, try to positively influence their loved once. It is very inspiring:)
Like Roxanne and Slacker mentioned, there are many discussions on MTHFR on the forum. If you would like to do a specific search please clink on the three stacked up squares next to your user name and select the search option.
I agree that significant changes are very difficult but base on what I have read, you have already done a lot of work! You have a right mindset and understanding. Further, needed changes apply slowly - step by step- with no rush. If you think, it would be beneficial to your health to remove grains, do it slowly and please substitute lost fiber with varieties of vegetables and low sugar fruits. Not all grains contain gluten/lectins, sorghum is excellent as well as reasonable amounts of millet or rice:). If you find deficiencies typical for Mthfr polymorphism beside customized supplements, try to saturate your diet in foods rich in those nutrients. I always say try to focus on what you can eat verses what you cannot:)
Dr. Ben Lynch's
book "Dirty Genes" is an excellent resource on how to "clean" your genes with diet and life-changes.
As for great new, inspiriting and flavorful recipes, I absolutely love Dr. Gundry's "The Plant Paradox Cookbook". His recipes are super delicious: https://gundrymd.com/books2/
It is not my intention to overwhelm you with a lot of information, so I am going to end here:)
If you have more detailed questions or concerns please write.
P.S. I have just noticed that Roxane's link to the PRIMER might not work, just incase, here it is again:viewtopic.php?f=33&t=1418