JohnThomas wrote:I just found out that I’m Apoe2/4 and I’m trying to figure some things out.
Although I have the 4 variant, I’m encouraged by the fact that even if I have maybe a 20% chance of AD, that means that I have an 80% chance of not getting AD. I’m 64 and I still have a great short-term and long-term memory.
Also, no one on either side of my family line has ever had AD or dementia or have ever died of heart disease.
So, given that I am ApoE 2/4, can anyone comment on what diet is best or direct me to some research on diet for 2/4?
Welcome, John! Your interpretation of what the odds are is the same way I like to look at them~ a 20 % chance of developing Alzheimer's is also an 80% chance of NOT developing it. You will see as you explore the site that within this community there is an strong underlying commitment to the idea that the epigenetic factors that are within our control can change the odds even more in favor of retaining cognitive health. I am happy to hear that your own memory is great both long and short term, and that you have no family history on either side of AD or dementia or death from heart disease.
An excellent place to get an overview of a lot of information on the ApoE4 allele is the Primer
, written and regularly updated by a physician member.
You can also use the Wiki
to get more in depth information in specific areas of interest, such as diet. There is not a unified approach to diet here. Rather, members are following different dietary guidelines and finding what works well for them individually. As far as I know, no one is posting specific recommendations for ApoE2/4's. The ApoE2 allele is generally regarded as protective, as you probably know. Here posts relate mainly to about how to counteract the risks of ApoE4.
The Wiki also includes a section with useful tips on how to get the most out of this website.
There is a search option, which you can access with the magnifying glass to the left of your user name or through the drop down menu that you'll get by clicking the three dots to the right of your name. That allows you to see all previous posts that contain your search word or phrase. (For example, there are 133 posts that appeared when I typed in ApoE2. )
We look forward to your participation on the forums. Please ask questions as they come up.
Again, a warm welcome to you!