WifeOfJoel wrote:I have high homocysteine (11.2), low-normal B12, normal serum folate (didn't check RBC folate), high RBC MCH, and a high serum vitamin B6 level (24.5, above the normal range of 2-21). I know the B6 test can be affected by vitamin consumption, but I don't think I took vitamins the day before, and I was fasting the day of the test.
Given that I am homozygous for the C677T MTHFR mutation, I know I have a methylation defect. I don't know what form of B6 the Quest Diagnostics test measures. Perhaps an increase measured vitamin B6 is seen in MTHFR patients, if the test is measuring the unmethylated form (that would build up presumably, as the methylation step is inefficient)?
Since getting my test results, I've started taking methyl folate and methyl B12. Do I need a special form of Vitamin B6, i.e., do I need to take pyridoxal-5-phosphate instead of pyridoxine hydrochloride?
WifeOfJoel wrote: and a high serum vitamin B6 level?
Its Me wrote:Also, you can go directly to SNPedia to see info. Here is rs5742950:WifeOfJoel wrote: and a high serum vitamin B6 level?
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