octicorn wrote:This is kind of an intro for my husband also; I don’t think he has posted here yet but we’ve been reading for months. I found out about this community in an article on consumer genetic testing and dug in, starting with the Primer, and I’ve been searching things as needed since then.
We are 39 (me) and 45 (him). Each of us had a grandmother with Alzheimer’s. His father was diagnosed a couple of years ago after experiencing mild cognitive issues requiring him to retire. The way we found out my husband’s genotype was sort of interesting: I was cleaning out old files and found a lab report from a doctor-ordered cholesterol test he had about 7 years ago, and noticed that there was genetic information in it. I recognized the APOE acronym from my previous reading about DNA testing for fitness and nutrition purposes, so I knew that it was related to Alzheimer’s. It reported a 4/4 result, but was only interpreted for him at the time in regard to cholesterol. So I showed it to him and it all became more real for us. We had actually been talking about getting 23andme done for both of us, mainly for health optimization, but we had been discussing how we would feel finding out about disease risks like this. Luckily, we had already been thinking we would prefer to know what there is to know.
To our great fortune, this website and its primer and its people already existed, so we have had hope along with our news every step of the way. The support I have seen here is beautiful. Thank you.
We were already familiar with LCHF/keto diets (he has been on a nearly lifelong weight loss journey), but after that we made further diet modifications such as reducing meat and saturated fat, and have worked harder on getting more frequent exercise and emphasizing cardio.
We both read The End of Alzheimer’s and I also bought a copy for his brother, and as luck would have it, their father picked it up while visiting the brother and read it immediately as well. He had already implemented many lifestyle changes when he retired, but I was truly surprised and happy that he would be so receptive to Dr. Bredesen’s book.
Since then, we’ve been layering on some of the more important/broadly recommended supplements from ReCode and Dr. Rhonda Patrick’s work and trying to get some initial lab tests done for him through Life Extension kits (scheduling the blood draw somewhere and getting it in the mail is proving a logistical hurdle).
Eventually I got curious enough (and also worked through my worries about health data privacy) to order myself a 23andme ancestry test and then run the report at FoundMyFitness. I was not surprised at all to find that I am 3/4. I’ve been mostly behaving as if that is the case up to this point. Now it mainly feels like we’re even more in the same boat than we were.
We have young kids, so it’s a struggle to spend as much time as I would like reading through all this information, but I’m trying to check back here regularly and listen to podcasts and keep learning. Thanks again.
octicorn wrote:... I've been lurking on forums for years ...
Its Me wrote:I wrote some of my thoughts to another post you can read, but I also like your idea of limiting saturated fat sources. I have great cholesterol - that ties to everything it seems like heart health and dementia - that I believe may relate to a diet for over a decade with oils and not solid added fats - butter is a treat when eating out occasionally. I eat skinless chicken and fish for meat nutrients, and once every week or 2 I have calves liver for a vitamin shot. My lipids are nicely low. And I also test Vitamin D, and take supplements 1000 twice a day that raised that from under 30 to 44 in 3 months when I retested. Quest Diagnostics now has a service where you can, in most states, order your own blood tests at reasonable cost if insurance does not cover.
octicorn wrote: … tracking one's own test results …
TheresaB wrote:I'm very grateful to have a spouse who's a 4 carrier. I find that since we're both aware and motivated, we support each other, are able to share information we discover, and can discuss issues with each other. I hope you have the same situation.
Its Me wrote:You can check your zip code to find the Quest location that does this in your area.
octicorn wrote:Unfortunately this brings up no locations near us. ,,,
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