R-Daughter wrote:Is there anyone else on this forum who has vascular dementia, not just recently diagnosed, and has made progress with this protocol? We three have done 23AndMe, and my father has one copy of e4.
Welcome aboard. I do not have Vascular Dementia, I do not know much about it, but your story touched my heart and I wanted to reach out to you. From my research, there does appear to be a connection between vascular dementia and ApoE4, although the connection is not as strong as the connection with Alzheimer’s Disease, nevertheless, there might be some nuggets you can gain from following us and/or asking questions.
As I understand it, Vascular Dementia is the result of cardiovascular disease impairing blood flow to the brain and often results after a stroke. I wonder if your father has been placed on statins (you don’t necessarily have to answer). But if yes, you might want to do some investigating and questioning as to the rationale behind that. I have a friend with a ZERO Coronary Artery Calcium (CAC) scan, i.e. NO calcium in artery walls, so virtually no risk for a cardiovascular event, but the medical folks concluded he should go on statins. The issue that precipitated this was a stroke. But the stroke was caused by a blood clot from an injury, when the clot broke loose he had a stroke. But all the medical profession saw was a stroke, therefore they concluded statins were in order. Fortunately, my friend evaluated the situation from a broader perspective and refused to go on statins.
I’m not saying statins are the devil’s workshop, they have their place, but I do feel they’re over prescribed ESPECIALLY in the older population. The brain is largely made of cholesterol, low cholesterol is associated with brain atrophy, and in older folks having high cholesterol seems to be a benefit.
According to this interview with Tommy Wood, http://www.nourishbalancethrive.com/pod ... nges-chol/
the older we get, the more protective cholesterol is, that high total cholesterol is only an issue when someone is younger. Data was taken from the Journal of Medical Insurance and where they had 1.5 million applicants for medical insurance and followed over an average of 12 years. They found for men above 60 years old the optimal reference range looks like 170 to 270, and in women, total cholesterol 200 to 300.
Just riffing here, some other articles:https://www.alzheimersresearchuk.org/be ... olesterol/https://www.webmd.com/cholesterol-manag ... der-peoplehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429025/
Okay, getting off that tangent. Mostly, I just wanted to say welcome and that I wish the best for your father. I personally know how difficult it an be to want the best for a loved one and my heart goes out to you as a caregiver. If nothing else, let it be known we care.