bladedmind wrote:I’m looking for authoritative documentation of Dr. Bredesen’s advice not to lower total cholesterol below 150. I’ve read the wiki entry on lipids several times. I need evidence for my cardiologist.
I’m 69 year old male, APOE 4/4, controlled hypertension, controlled T2D (H1Bac always 5.7), eating low carb (not keto), moderate protein, high good-fat diet. No heart attacks among mother (died at 93 with full mental faculties), father (died at 89 after several years of congestive heart disease and alzheimer’s), nor in two living brothers 10 and 14 years older (no Alzheimer’s either).
I had acute pericarditis 12 months ago and they saw a small lesion - not sure what that means. I had a cardiac stress test six months later and passed with flying colors - better than age.
In 2002 I tried Lipitor for a few months and ended up confused, fatigued, and depressed. Slowly recovered after quitting. In late 2017 because of physician pressure I tried pravastatin every other day. One day a few months later I was wandering around in my house and was able to figure out that my short-term memory had vanished - persistently I could not remember what I was doing or compose complex, linked thoughts. So I quit again and it took about six weeks to get back to baseline. Now, despite this history, the heart doctor wants me to go on rosuvastatin every other day, and I am afraid because I do complex intellectual work.
I do have one blood reading from the pravastatin period:
130 TC, 22 HDL, 83 LDL, 125 TG
My TC was below 150 and a few months later my short-term memory did not function.
Since my most recent total cholesterol reading is 182 (and my 10-year average 186), I’m worried that the rosuvastatin will drive it below 150 against APOE 4/4 advice.
I’ve been doing most of the Bredesen protocol on my own, skipping remedies that I don’t tolerate well, and I think as a result my memory is great right now.
I am looking at eight blood tests for the last 10 years (and my vague memory is that I have always had high triglycerides - genetic?): Readings are consistently similar, through bad diet and good diet, no change with age. I have a terrible TG/HDL ratio.
Omitting the pravastatin outlier, so 7 tests
Range 172-228, only one reading above 200.
Range 181-400, all over 170
Through nursing error I had a nonfasting blood test in June 3, 2018
155 TC, 34 HDL, 92 LDL, 144 TG
A fasting blood test on June 15, 2018 was quite different.
182 TC, 22 HDL, 109 LDL, 257 TG
Does that discrepancy mean anything?
Thanks in advance for your help.
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