Rs7412
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Rs7412
Why if I’m a 4/4 would my Rs7412 show no clinical abnormalities?
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Re: Rs7412
The graph is showing that Rs7412 with C/C alleles by itself doesn't prove you have ApoE 4/4. However, as this quote below shows, it all depends on who its neighbors are:Jcmainfinity wrote:Why if I’m a 4/4 would my Rs7412 show no clinical abnormalities?
https://www.selfdecode.com/snp/rs7412/If the allele of this SNP is "C" and the same chromosome also harbors the rs429358 "C" allele, the combination is known as an APOE-ε4 allele.
SNPedia has a good chart on this page https://www.snpedia.com/index.php/APOE that shows how the various combinations of the two key alleles result in several different ApoE results.
4/4 and still an optimist!