Hi pinkgothic,pinkgothic wrote:Just an update (not expecting comments on this, just felt appropriate to update):
....My B12 values are up from 142 ng/l to 311 ng/l. This is on a heavy meat diet and supplements, so I'm going to apply More Dakka on the supplement side, but dial back on the meat, and see what happens. Going to have another lab test in September, focus is on vitamin D, but I'll also let them test B12 again (and hopefully a host of other cognoscopy attributes).
And to help you navigate this site, here's a link to our "How-To" Get the most out of the ApoE4.info website.In addition, low B12 levels have been associated with greater incidence of dementia. This is not controversial. It may be that "normal" reference ranges may be set too low for optimal cognitive health. Many of our members run their B12 levels at the upper limit of "normal" , not the lower.
NF52 wrote:Although your B12 levels would now be considered within the "normal" range, I wanted to share my experience as a participant in a study of healthy people ages 60-75 who have one or two copies of ApoE 4 (I have two and am 67 years old.) My B-12 level on testing in March 2018 was 426. It had never been tested by my primary care providers so this is my "baseline". The Senior Investigator/Study Doctor recommended that I start taking a daily lozenge of 500 mcg of methylcobalamin to get the level about 500. (500 is also what Dr. Bredesen recommends as a minimum.)
NF52 wrote:I order mine online, and would hope that it's possible for you to order it in Hamburg. Here's a link I found for Jarrow Deutschland's 500 mcg lozenge. Jarrow happens to be the company I order from; they just happened to also come up when I Googled "methylcobalamin Germany": https://www.jarrow.de/en/vitamins/19-jarrow-methyl-b-12-500-g.html
NF52 wrote:Six months after I added B-12, my B-12 level was 644 and in March 2019 it was 672. I would strongly recommend that you consider supplementing with methylcobalamin to get your B-12 above 500. Here's our physician/Primer author Stavia in the Primer:Supplements on the importance of B12:And to help you navigate this site, here's a link to our "How-To" Get the most out of the ApoE4.info website.In addition, low B12 levels have been associated with greater incidence of dementia. This is not controversial. It may be that "normal" reference ranges may be set too low for optimal cognitive health. Many of our members run their B12 levels at the upper limit of "normal" , not the lower.
buck3Maureen wrote:Hello Pinkgothic,
Just read this thread and I want to welcome you.
buck3Maureen wrote: I am your mom's age and started having symptoms about 7 or 8 years ago that gradually got worse. Before the Bredesen book came out I was lucky enough to get a copy of his scientific study that briefly outlined many of the "36 Holes" that he describes in his book. Then I was fortunate to attend a week long seminar by Dr. Bredesen. This included meeting with a nutritionist. I feared that she would telI me that i would have to ditch my Vegan diet, I was told, no, it was not necessary. Everyone is different so for others this may not work. I have improved immensely over that past few years and I am hopeful that I will not succumb to AD, or that it will be pushed into the far distant future.
buck3Maureen wrote: I don't know if you were born and raised in Germany, but I am totally amazed by your English skills. As part of the program that challenges your brain I decided to try and learn German. As someone who never knew a foreign language ( I took Latin in HS) I have a deep appreciation for this skill. I think I will try and get a copy of his book written in German!
buck3Maureen wrote:On the other hand I dropped a lot of the supplements that I was taking and it did not seem cause a problem.
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