E4 and AMD

Newcomer introductions, personal anecdotes, caregiver issues, lab results, and n=1 experimentation.
Nikki2019
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E4 and AMD

Postby Nikki2019 » Wed Dec 18, 2019 9:40 pm

I also have 3 variants for AMD, as per 23andme. I found this online, which looks like E4s have at least this going for us... seems to indicate it is protective :D for AMD?
http://www.amdbook.org/content/genetics-amd
As E4 s, we are inherent fighters and don't give up so easily.

thjj
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Re: E4 and AMD

Postby thjj » Thu Dec 19, 2019 11:11 pm

Interesting, my friend recently told me that she has AMD & her eyesight has been getting worse every year. I recently told her that I'm E4/4!
· • She/her · • ·
ApoE4/4 status known: 2018 | Born: 1969 | Cognitive Impairment: none

Nikki2019
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Re: E4 and AMD

Postby Nikki2019 » Sat Dec 21, 2019 9:51 pm

The study that plans to replace a 4 with a 2 doesn't want to replace both 4s of the participants because of any potential benefits of the 4. So, I stumbled upon one that directly applies to me! If you scroll down to the portion that speaks to ApoE, it mentions that most studies show a protective factor of having a 4 of keeping ones sight. It is pretty frightening to think of myself of both blind and demented. So, I hold on to any hope I get! :lol:
As E4 s, we are inherent fighters and don't give up so easily.


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