I also have 3 variants for AMD, as per 23andme. I found this online, which looks like E4s have at least this going for us... seems to indicate it is protective for AMD?
http://www.amdbook.org/content/genetics-amd
E4 and AMD
E4 and AMD
As E4 s, we are inherent fighters and don't give up so easily.
Re: E4 and AMD
Interesting, my friend recently told me that she has AMD & her eyesight has been getting worse every year. I recently told her that I'm E4/4!
· • She/her · • ·
ApoE4/4 status known: 2018 | Born: 1969 | Cognitive Impairment: none
ApoE4/4 status known: 2018 | Born: 1969 | Cognitive Impairment: none
Re: E4 and AMD
The study that plans to replace a 4 with a 2 doesn't want to replace both 4s of the participants because of any potential benefits of the 4. So, I stumbled upon one that directly applies to me! If you scroll down to the portion that speaks to ApoE, it mentions that most studies show a protective factor of having a 4 of keeping ones sight. It is pretty frightening to think of myself of both blind and demented. So, I hold on to any hope I get!
As E4 s, we are inherent fighters and don't give up so easily.