Russ wrote: Is it possible to resolve the glucose/lipid challenge through variability? Feels like an interesting N=1 experiment, but hard to resolve, and not sure I have the time and patience to do.
Along the lines of Kiefer's Carb Nite & Carb Backloading, I presume. His sidekick, Dr. Rocky (Patel), probably has more experience with this approach clinically than anyone. Rocky doesn't worry about ApoE unless they have a bad family history.
My home tester (CardioChek) will go off scale low for Tg's (<50) the morning after a Carb Nite. Some serial Tg testing after eating fat suggests a longer time to clear Tg's from my system than normal (normal is a spike followed by a decline). Most normals will be at baseline after 12 hours. I can take 16 to 20 hours. The results from an NMR after a Carb Nite were essentially the same as from a 36 hour fast - LDL-P ~1300 small LDL-P 230. My most recent NMR after six months on the high EVOO, no animal or dairy fat except omega 3 eggs, shell & white fish and 3 months on 1 g/day Slo-Niacin was LDL-P 1289, small LDL-P <90 (off scale low).
This probably means I could do a very low fat vegan diet with higher carbs and have good results, though I have autoimmune issues with grain & legume proteins.