At the 6 year mark into vegan dieting (following 3 decades of lacto-vegetarianism), got an advanced lipid panel for the first time, not via NMR but ion mobility fractionation. Does anyone here consider that method as accurate as NMR?
Tc=173, HDLc=42, TG=120, LDLc=107, Tc/HDL=4.1, non-HDLc=131
LDL particle number=1139 (considered optimal by the Quest diagnostic lab whose reference range is 1016-2185), LDL small=260 (high risk), LDL medium=215 (moderate risk), HDL large=4311 (high risk), LDL pattern=B (high risk), LDL peak size=210.3 angstrom (high risk), Apolipoprotein B=91 (moderate risk), Lipoprotein (a)=72 (optimal)
Was testing a diet including daily consumption of some refined grains and added sugars, and that must have contributed to the highest TG number i’ve seen for me, not to mention the first high fasting glucose (102) i’ve seen, though A1c came in at 5.5, not pre-diabetic. Sticking with mostly complex carbs looks like a healthier path for me.
Oils i was eating included red palm oil, canola vegenaise, and Earth Balance buttery spread (palm, canola, safflower, flax, evo). Doesn’t look like there was enough tocotrienols in the red palm oil to counteract the LDL-raising effect of the saturated fat in it. Saturated fat bumps up HDL but it also is known to impair insulin resistance, so i might have gotten better results not using the red palm oil.
Was getting about 60% of calories from carbs, 30% from fat (7% saturated), 10% from protein. After this test i discovered i’m an apoE-3/4, so my present direction is to move toward the suggestion for that genetic group given at http://gg.gg/apoE-macro-guide
-- 55% carb, 25% protein, 20% fat, or maybe 60-20-20.
TG/HDLc=120/42 (2.86). My ratio was closer to where it should be -- 83/40 (2.07) on last year’s test when i was testing fatty whole plant food and no refined flours or added sugars. The TG/HDL ratio was better still 2 tests ago in 2012, 64/44 (1.45) when my body weight was lowest. Since that ratio is said to predict LDL particle size, i started to think that i likely had the optimal LDL pattern A in 2012, but after reviewing the case study http://gg.gg/apoE-cs-3
i’m less inclined to think that since the lady had a superb TG/HDL ratio but still had lots of small particles. Has anyone here successfully converted an LDL pattern B into pattern A? Is that as doable as is lowering LDL-c? Paleo promoters make the blanket statement that more fat and less carbs will increase LDL particle size but there are studies showing low fat diets reducing levels of small, dense LDL for apoE 4 people: http://gg.gg/apo-E
Peter Attia makes the case at http://gg.gg/LDL-number
that it’s particle number and not size that drives atherosclerosis. If he’s right, i might be alright at present if the ion mobility fractionation test method is sound, since my particle number is now optimal according to that test method. Attia says “Virtually all guidelines (e.g., ADA, ACC, AACC and NLA) only advise LDL-P via NMR at this time.”