From Dr. Robert Mahley

Insights and discussion from the cutting edge with reference to journal articles and other research papers.
ApropoE4
Contributor
Contributor
Posts: 332
Joined: Sun Feb 02, 2014 10:43 pm

Re: From Dr. Robert Mahley

Postby ApropoE4 » Sun Oct 04, 2015 8:06 pm

Gilgamesh wrote: But are we certain the correction would only take place outside neurons? (1) suggests possibly not, but I read the paper two years ago and I don't have the original with me right now.


Iirc, mitochondrial function restoration was only measured in culture. I'm guessing the researchers are aware of a shortfall when it comes to correcting apoe4 inside neurons, or they wouldn't be concerned with a separate process to restore mito function, right?

Lucy5
Support Team
Support Team
Posts: 302
Joined: Sat Oct 03, 2015 10:52 am
Location: Colorado

Re: From Dr. Robert Mahley

Postby Lucy5 » Tue Oct 13, 2015 11:05 am

Bob Mahley is my hero. After I leaned my Apoe4 status I found the Gladstone group and reached out to him, NEVER thinking he'd respond to my email. My best hope - someone on his staff. But he did. In addition to being the brilliant researcher and leader in his field that we all know him to be, he is so compassionate.

I am fascinated by his work with the structure corrector and feel that for those of us who are 4/4, it may be the best way forward. An elegant solution. He gives me hope.

Online
User avatar
Stavia
Mod
Mod
Posts: 4531
Joined: Tue Apr 29, 2014 6:47 pm
Location: Middle Earth

Re: From Dr. Robert Mahley

Postby Stavia » Tue Oct 13, 2015 12:08 pm

We met him earlier this year. Such a kind, humble man. Totally gorgeous.

User avatar
Gilgamesh
Mod
Mod
Posts: 1662
Joined: Sat Oct 26, 2013 11:31 am
Location: Northeast US mostly
Contact:

Re: From Dr. Robert Mahley

Postby Gilgamesh » Tue Oct 13, 2015 2:34 pm

Lucy, he's my hero, too. ApropoE4: we need to get the paper and refresh our memories!

GB


Return to “Science and Research”

Who is online

Users browsing this forum: No registered users and 2 guests