Brand new to group - 1st post

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jkramer65
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Re: Brand new to group - 1st post

Postby jkramer65 » Thu Dec 06, 2018 11:55 am

Fiver wrote:Hello JKramer65. Sending warm wishes your way. You got a "surprise" from the side of the family where we might have counted on a E3 or E2. What you're feeling is very normal.

It might help to know that there are many other genes and environmental factors other than E4 that play a role. Given that most of your family members were diagnosed with AD so late in life I would suspect that you also have some protective genes mixed in there....ones we don't even know about yet. Plus, you have this knowledge, this site, and modern medicine on your side.

I can say that the shock and worry does get better over time. And if you can use some of it as motivation to learn what you can and make changes to reduce your risk (and improve your overall health) then something positive comes from it.



UPDATE! Got my mother's results from 23 and me. I thought she might be e2/e4 but she is e3/e4 so curious what is in her genes to have prevented AD. She turns 92 on January 18! I'll never know my dad's (if he had one or two e4s). unless i take some of his ashes to a lab i suppose! lol. I'd be interested in in he was e4/e4. On Monday I'll know my recently diagnosed sister's status. She is meeting with a genetic counselor for a DNA review. I'll be listening in via phone. Should be interesting.

Thought you would all want to know!
Jane

mike
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Re: Brand new to group - 1st post

Postby mike » Thu Dec 06, 2018 3:13 pm

jkramer65 wrote:UPDATE! Got my mother's results from 23 and me. I thought she might be e2/e4 but she is e3/e4 so curious what is in her genes to have prevented AD. She turns 92 on January 18!
Jane


Jane, e3/e4s risk for Alzheimer's is nowhere near as high as for e4/e4s, and can often be overcome by lifestyle choices...
Sonoma Mike
4/4

jkramer65
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Re: Brand new to group - 1st post

Postby jkramer65 » Thu Dec 06, 2018 3:59 pm

mike wrote:
jkramer65 wrote:UPDATE! Got my mother's results from 23 and me. I thought she might be e2/e4 but she is e3/e4 so curious what is in her genes to have prevented AD. She turns 92 on January 18!
Jane


Jane, e3/e4s risk for Alzheimer's is nowhere near as high as for e4/e4s, and can often be overcome by lifestyle choices...


RIGHT. And she has lived a life that should have given her AD long ago. That is why there has to be something protecting her. After all she has NEVER exercised, smoked for 50 years, ate like shit, drank like a fish. I could go on. Oh yeah, she is morbidly obese.

My dad who had AD did everything right and got it.

mike
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Re: Brand new to group - 1st post

Postby mike » Fri Dec 07, 2018 10:49 am

jkramer65 wrote:After all she has NEVER exercised, smoked for 50 years, ate like shit, drank like a fish. I could go on. Oh yeah, she is morbidly obese.


Go figure. Well, if she does have a protecting gene, I hope they find it! Your dad may have been a 4/4. Since he died in 2011, much has been learned about Alzheimer's. I'm also 4/4, and I don't plan to die from it. I believe I'll be able to keep it at bay until better treatment comes. If not, it tends to hit my family in the 80s or 90s, so I should still have many good years left.
Sonoma Mike
4/4

jkramer65
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Re: Brand new to group - 1st post

Postby jkramer65 » Fri Dec 07, 2018 12:03 pm

mike wrote:
jkramer65 wrote:After all she has NEVER exercised, smoked for 50 years, ate like shit, drank like a fish. I could go on. Oh yeah, she is morbidly obese.


Go figure. Well, if she does have a protecting gene, I hope they find it! Your dad may have been a 4/4. Since he died in 2011, much has been learned about Alzheimer's. I'm also 4/4, and I don't plan to die from it. I believe I'll be able to keep it at bay until better treatment comes. If not, it tends to hit my family in the 80s or 90s, so I should still have many good years left.


I'm with you brother! I'm a 4/4 who will march to a different beat as well! We will see what my sister is on Monday. My dad lived until he was 87 so that doesn't suck. Only the last couple of years were bad -- and not for him but for us as caretakers. I do know women tend to get it earlier than men but I'm going to buck that tradition as well! Good luck to us both. Cheers!

mike
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Re: Brand new to group - 1st post

Postby mike » Fri Dec 07, 2018 12:17 pm

jkramer65 wrote:I do know women tend to get it earlier than men but I'm going to buck that tradition as well! Good luck to us both. Cheers!


Men tend to get Cardio Vascular issues first and die from that rather than AD...I had a stroke 4 years ago, but "only" a minor one.
Sonoma Mike
4/4

jkramer65
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Re: Brand new to group - 1st post

Postby jkramer65 » Fri Dec 07, 2018 12:31 pm

mike wrote:
jkramer65 wrote:I do know women tend to get it earlier than men but I'm going to buck that tradition as well! Good luck to us both. Cheers!


Men tend to get Cardio Vascular issues first and die from that rather than AD...I had a stroke 4 years ago, but "only" a minor one.


It is always something!


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