I am also a 2/4. My searching has led me to conflicting information, probably because we are too rare to study. It seems that the keto 12/3 is best. My triglycerides cut in half and my HDL went up. LDLc went up but small particle size isn't too bad. I suggest Calcium CT scoring. Mine was a little high in 2017 so I will retest in another year or so since it's a lot of radiation.Sara wrote:Greetings Linda and welcome to the apoe4.info site! There is some excellent information about nutrition in the Primer which was written by Stavia, a physician, member and E4/E4. Congratulations for being on top of your status and researching the best nutritional plan for you! It might help if you were to share a little more of you story... and you can do this on Our Stories... for instance your age, symptoms and any medical concerns. Many on this site are following Dr. Bredesen's Ketoflex 12/3 plan but this is a highly personalized decision and it would be helpful to work with someone trained in these nutritional protocols albeit a practitioner, nutritionist or health coach. Warm Regard!
KennaH wrote:I'm also 2/4, and just joined. Like you, I am finding it hard to pin down what is best for my type.
ApoE2 and apoE4 increase the risk for heart disease: apoE2 increases atherogenic lipoprotein levels (it binds poorly to LDL receptors), and apoE4 increases LDL levels (it binds preferentially to triglyceride-rich, very low density lipoproteins, leading to downregulation of LDL receptors).
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